Ignite Creation Date:
2024-05-06 @ 2:15 PM
Last Modification Date:
2024-10-26 @ 1:27 PM
Study NCT ID:
NCT04260724
Status:
UNKNOWN
Last Update Posted:
2020-02-07
First Post:
2020-01-22
Brief Title:
Study on the Effect of Transcranial Magnetic Stimulation in Mild to Moderate Alzheimers Disease
Sponsor:
Samsung Medical Center
Organization:
Samsung Medical Center
Study Overview
Official Title:
Prospective Randomized Evaluator-blind Single Center Study on the Effect of Transcranial Magnetic Stimulation in Mild to Moderate Alzheimers Disease
Status:
UNKNOWN
Status Verified Date:
2020-02
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The investigators will compare cognitition mood depression ADL and brain structural and functional MRI before and after 4-week transcranial magnetic stimulation in patients with mild to moderate Alzheimers disease
The investigators also compare the change of cognitition mood depression ADL and brain structural and functional MRI between TMS group and sham coil group
The investigators also compare the change of cognitition mood depression ADL and brain structural and functional MRI between TMS group and sham coil group
Detailed Description:
Each 16 patients will be allocated to TMS group and sham coil group Before TMSsham coil stimulation the investigators will take fMRI of each patient and figure out which focus has strongest connectivity to hippocampus among lateral parietal regions of the brain The investigators will fix the TSM transduced and apply accurate TMS stimulation to the focus using personalized frames The investigators will make the frame using 3D printing technology
After 4 week- TMS stimulation the investigators will compare cognitition mood depression ADL and brain structural and functional MRI beween baseline and after intervention The investigators also compare the change of cognitition mood depression ADL and brain structural and functional MRI between TMS group and sham coil group
After 4 week- TMS stimulation the investigators will compare cognitition mood depression ADL and brain structural and functional MRI beween baseline and after intervention The investigators also compare the change of cognitition mood depression ADL and brain structural and functional MRI between TMS group and sham coil group
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None