Ignite Creation Date:
2024-05-06 @ 2:14 PM
Last Modification Date:
2024-10-26 @ 1:27 PM
Study NCT ID:
NCT04254432
Status:
UNKNOWN
Last Update Posted:
2020-02-05
First Post:
2020-01-22
Brief Title:
Safety and Feasibility of Remote Ischemic Conditioning on Prehypertension and Early-stage Hypertension
Sponsor:
Capital Medical University
Organization:
Capital Medical University
Study Overview
Official Title:
Safety and Feasibility of Remote Ischemic Conditioning on Prehypertension and Early-Stage Hypertension
Status:
UNKNOWN
Status Verified Date:
2020-02
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Nowadays the incidence of stroke in China has reached 16 and this disease has become a primary cause of death in China One of its major risk factors is hypertension As shown in the researches the risk of stroke grows remarkably when the blood pressure increases and there exists a log-linear relationship between them Systolic pressure and diastolic pressure relate to the risk of stroke independently Systolic pressure decreasing 10mmHg will reduce the stroke risk by 31 and a decrease of 13mmHg will reduce the stroke risk by2030 As to diastolic pressure a 5mmHg decrease will reduce the stroke risk by 34 and a 10mmHg decrease will reduce the stroke risk by 56In addition patients with isolated systolic hypertension SPB160mmHg DPB90mmHg or critical isolated systolic hypertension SPB140159mmHg DPB 90mmHg will suffer a higher risk of stroke than people with normal blood pressure The ACC has already revised its Hypertension ManagementGuidelines of the standard of diagnosis for hypertension and the timing of starting medical treatment in hypertensive patients Because more and more researches shown that people with blood pressure between 120-13980-89mmHg have higher risk of ASCVSD compared to those with blood pressure lower than12080mmHg However in China the diagnostic criteria for hypertension has not been revised yet Therefore we still have a blind spot in treating such patients who suffer from borderline systolic hypertension at 130140 mmHg of blood-pressure with or without ASCVD or those with the first stage hypertension but refusing to take anti-hypertension drugs What is more most of them are middle-aged adults once they have a stroke it would lead to terrible and costly consequences to both their family and society Thus it is necessary to explore new non-pharmacological methods to control blood pressure for reducing the risk of stroke
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None