Ignite Creation Date:
2024-05-06 @ 2:12 PM
Last Modification Date:
2024-10-26 @ 1:26 PM
Study NCT ID:
NCT04245787
Status:
UNKNOWN
Last Update Posted:
2020-01-29
First Post:
2020-01-27
Brief Title:
Remineralization Potential of Curodont Repair Flouride Plus Versus CPP-ACP in Management of White Spot Lesions Randomized Clinical Trial
Sponsor:
Cairo University
Organization:
Cairo University
Study Overview
Official Title:
Remineralization Potential of Curodont Repair Flouride Plus Versus CPP-ACP in Management of White Spot Lesions Randomized Clinical Trial
Status:
UNKNOWN
Status Verified Date:
2020-01
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of modern dentistry is to manage non-cavitated caries lesions non- invasively through re-mineralization process to prevent the disease progression and improve aesthetics strength and function Re-mineralization is defined as the process that supplies calcium phosphate and flouride ions from an external source to the tooth to convert ion deposition into crystal voids in demineralized enamel White spot lesions should be managed using a multifactorial approach The most important strategy is to prevent demineralization and biofilm formationand use of methodologies for remineralization of lesions
Self-assembling peptide P11-4 has shown great potential for natural repair of early caries lesions through emerging biomimetic re-mineralization properties Takahashi Fet al in 2015 This peptide forms a 3D matrix within demineralized carious lesions areas which enables novo hydroxyapatite crystal formation facilitating the so-called guided enamel regeneration of the lost enamel structure The peptide has shown encouraging results as a scaffold for enamel regeneration
Self-assembling peptide P11-4 has shown great potential for natural repair of early caries lesions through emerging biomimetic re-mineralization properties Takahashi Fet al in 2015 This peptide forms a 3D matrix within demineralized carious lesions areas which enables novo hydroxyapatite crystal formation facilitating the so-called guided enamel regeneration of the lost enamel structure The peptide has shown encouraging results as a scaffold for enamel regeneration
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None