Ignite Creation Date:
2024-05-05 @ 11:19 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001229
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Diagnosis and Treatment of Pheochromocytoma
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Diagnosis and Treatment of Pheochromocytoma
Status:
COMPLETED
Status Verified Date:
1999-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Pheochromocytoma is a tumor of the adrenal gland This tumor is typically benign not cancerous and can be cured by surgical removal However pheochromocytomas produce neurohormones called cateholamines epinephrine and norepinephrine High levels of catecholamines can result in high blood pressure headaches sweating heart palpitations nausea vomiting and other symptoms These tumors are considered dangerous because of their unpredictable behavior Patients with pheochromocytoma may experience blood pressures high enough to cause a stroke or heart attack in patients
This study is designed to take patients suspected of having pheochromocytoma and confirm the diagnosis This will be done using a variety of laboratory tests including a clonidine suppression test and glucagon stimulation test These tests use drugs that can stimulate or reduce the activity of the tumor if it is present in the body
Once a diagnosis is confirmed patients participating in this study will undergo standard procedures to find the exact location of the tumor and receive standard therapy for the condition
This study is designed to take patients suspected of having pheochromocytoma and confirm the diagnosis This will be done using a variety of laboratory tests including a clonidine suppression test and glucagon stimulation test These tests use drugs that can stimulate or reduce the activity of the tumor if it is present in the body
Once a diagnosis is confirmed patients participating in this study will undergo standard procedures to find the exact location of the tumor and receive standard therapy for the condition
Detailed Description:
Patients suspected of having a pheochromocytoma will be studied via a series of tests in an attempt to ascertain biochemically whether or not they really have such a tumor These procedures will include a standard clonidine suppression test and a standard glucagon stimulation test Once the diagnosis has been made on the basis of biochemistry then localization and therapy will be done via standard procedures Measurement of plasma metanephrines on mailed samples is available for physicians who seek further evidence for the diagnosis of pheochromocytoma
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 88-H-0189 | None | None | None |