Ignite Creation Date:
2024-05-06 @ 2:07 PM
Last Modification Date:
2024-10-26 @ 1:25 PM
Study NCT ID:
NCT04227548
Status:
COMPLETED
Last Update Posted:
2020-01-13
First Post:
2020-01-09
Brief Title:
Reference Values for Compound Muscle Action Potential Amplitude Obtained by Direct Muscle Stimulation
Sponsor:
Adana City Training and Research Hospital
Organization:
Adana City Training and Research Hospital
Study Overview
Official Title:
Reference Values for the Ratio of Compound Muscle Action Potential Amplitude Obtained by Nerve Stimulation to That Obtained by Direct Muscle Stimulation
Status:
COMPLETED
Status Verified Date:
2020-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Direct muscle stimulation DMS method is one of the electrodiagnostic methods used in the diagnosis of critical illness myopathy CIM and critical illness neuropathy CIN The ratio of amplitude of compound muscle action potential CMAP obtained by nerve stimulation nCMAP to amplitude of CMAP obtained by DMS dmCMAP can be used to differentiate these two diseases Although not certain if the ratio is 05 the diagnosis is thought to be consistent with CIN The ratio 05 is considered to be a finding supporting CIM The investigators aimed to find the reference values of the ratio from healthy individuals A monopolar needle electrode was used for DMS The dmCMAP and nCMAP were recorded with a concentric needle The ratio was calculated by using amplitudes of dmCMAP and nCMAP obtained from deltoid and tibialis anterior muscles
Detailed Description:
Age gender height weight body mass index and neurological examination findings of the participants were recorded Healthy participants were not included if they had polyneuropathy or a disease such as diabetes mellitus that causes polyneuropathy complaints such as weakness or paresthesia a neurodegenerative disease abnormal neurological examination myopathy or hereditary polyneuropathy in family history In addition healthy participants were excluded if the conventional nerve conduction study and needle electromyography EMG findings were abnormal Median ulnar posterior tibial peroneal superficial peroneal sural nerve conduction studies were performed to all participants Needle EMG and direct muscle stimulation were applied to the deltoid and tibialis anterior muscles of the healthy participants
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None