Ignite Creation Date:
2024-05-06 @ 1:59 PM
Last Modification Date:
2024-10-26 @ 1:22 PM
Study NCT ID:
NCT04172870
Status:
UNKNOWN
Last Update Posted:
2020-02-20
First Post:
2019-11-20
Brief Title:
Evaluation of Inflammatory Markers and Periodontal Viruses on Periodontitis Patients With CAD
Sponsor:
Meenakshi Ammal Dental College and Hospital
Organization:
Meenakshi Ammal Dental College and Hospital
Study Overview
Official Title:
Evaluation of Demographic Variables Clinical Parameters Inflammatory Markers and Viruses in Periodontitis Patients With Coronary Artery Diseases
Status:
UNKNOWN
Status Verified Date:
2020-02
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To assess and compare the demographic variables periodontal parameters cardiac parameters and the expression of periodontal viruses CMV HSV and EBV and inflammatory biomarkersPTX-3 TLR-2 TLR-4 in periodontally healthy and generalized periodontitis patients with and without coronary artery diseaseCAD
Detailed Description:
A total of 240 subjects will be recruited based on the power of the study The selected subjects will be divided into four groups based on the inclusion and exclusion criteria
1 GROUP I 60 healthy subjects No generalised periodontitis and no CAD
2 GROUP II 60 generalised periodontitis subjects without CAD
3 GROUP III 60 CAD subjects without generalised periodontitis
4 GROUP IV 60 subjects with Generalised periodontitis and CAD
Sub-gingival plaque samples will be collected from the subjects of all the four groups Coronary artery plaque samples will be collected from the patients who were indicated for coronary artery bypass graft surgery CABG among group III and group IV
The demographic variables periodontal parameters cardiac parameters expression of periodontal viruses and inflammatory biomarkers will be measured in all four groups
1 GROUP I 60 healthy subjects No generalised periodontitis and no CAD
2 GROUP II 60 generalised periodontitis subjects without CAD
3 GROUP III 60 CAD subjects without generalised periodontitis
4 GROUP IV 60 subjects with Generalised periodontitis and CAD
Sub-gingival plaque samples will be collected from the subjects of all the four groups Coronary artery plaque samples will be collected from the patients who were indicated for coronary artery bypass graft surgery CABG among group III and group IV
The demographic variables periodontal parameters cardiac parameters expression of periodontal viruses and inflammatory biomarkers will be measured in all four groups
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| FLLIRC012017 | OTHER | Frontier Lifeline Hospital | None |