Ignite Creation Date:
2024-05-06 @ 1:57 PM
Last Modification Date:
2024-10-26 @ 1:22 PM
Study NCT ID:
NCT04170205
Status:
UNKNOWN
Last Update Posted:
2019-11-20
First Post:
2019-11-13
Brief Title:
Causes Associated With Small Fiber Neuropathy SFN
Sponsor:
University Hospital Brest
Organization:
University Hospital Brest
Study Overview
Official Title:
Retrospective Study of Causes Associated With Small Fiber Neuropathies
Status:
UNKNOWN
Status Verified Date:
2019-10
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
EtioNPF
Brief Summary:
Small fiber neuropathy SFN is an injury of cutaneous nerve fibers mainly by a decrease in their density within the cutaneous tissue The symptomatology associated with this SFN is broad with symptoms that are essentially sensory but also autonomic The etiologies of SFN are numerous diabetes drug infectious immunological and clinically non-specific justifying a broad etiological assessment The appearance of staged skin biopsies in the SFN balance sheet has greatly helped to improve diagnosis
Despite this a significant part of SFN remains without associated etiology and is considered idiopathic
As the distribution of the different causes of SFN remains a missing data to date the completion of this cohort study by one of the SFN reference centres should make it possible to establish the prevalence of SFN causes over a large population
Only patients with clinical symptoms that may be related to SFN and who have been sampled for SFN positive or not will be eligible for recruitment
The result of the anatomopathological sampling will allow patients to be separated into two groups with or without SFN
The main judgement criteria will be the prevalence of etiologies associated with SFN diabetes medication systemic lupus erythematosus Gougerot-Sjögren syndrome amylosis dysthyroidism alcoholism vitamin B12 deficiency HIV infection hepatitis C paraneoplastic syndrome hereditary disease Fabry disease Friedreich ataxia idiopathic others
Despite this a significant part of SFN remains without associated etiology and is considered idiopathic
As the distribution of the different causes of SFN remains a missing data to date the completion of this cohort study by one of the SFN reference centres should make it possible to establish the prevalence of SFN causes over a large population
Only patients with clinical symptoms that may be related to SFN and who have been sampled for SFN positive or not will be eligible for recruitment
The result of the anatomopathological sampling will allow patients to be separated into two groups with or without SFN
The main judgement criteria will be the prevalence of etiologies associated with SFN diabetes medication systemic lupus erythematosus Gougerot-Sjögren syndrome amylosis dysthyroidism alcoholism vitamin B12 deficiency HIV infection hepatitis C paraneoplastic syndrome hereditary disease Fabry disease Friedreich ataxia idiopathic others
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None