Ignite Creation Date:
2024-05-06 @ 1:55 PM
Last Modification Date:
2024-10-26 @ 1:22 PM
Study NCT ID:
NCT04169516
Status:
COMPLETED
Last Update Posted:
2019-11-20
First Post:
2019-11-14
Brief Title:
Localization of Microvascular Dysfunction
Sponsor:
Dong-A University
Organization:
Dong-A University
Study Overview
Official Title:
Different Microcirculation Response to Ischemic Injury of Culprit and Non-culprit
Status:
COMPLETED
Status Verified Date:
2019-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Microvascular dysfunction is an independent predictor of poor prognosis Such response in the culprit vessel is common even after successful revascularization This study investigated whether the microvascular dysfunction differed between culprit and non-culprit vessels in patients with acute coronary syndrome ACS who underwent percutaneous coronary intervention PCI
Detailed Description:
The prospective study included 115 patients with ACS In this study after successful PCI culprit and non-culprit intracoronary hemodynamic measurements were performed and repeated at 6-month follow-up 13N-ammonia positron emission tomography PET was performed at 6-month follow-up visit to determine absolute myocardial blood flow MBF The resistance values of each vessel were calculated using the coronary pressure data and the MBF values obtained from 13N-ammonia PET data Such physiological measures were compared between culprit and non-culprit vessels in baseline and 6-month follow-up
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None