Ignite Creation Date:
2024-05-06 @ 1:53 PM
Last Modification Date:
2024-10-26 @ 1:22 PM
Study NCT ID:
NCT04157556
Status:
COMPLETED
Last Update Posted:
2020-04-30
First Post:
2019-11-05
Brief Title:
The Effect of Maximal Exercise on MMP9 and TIMP1 and The Role of MMP9 -1562 CT and TIMP1 372 TC Polymorphisms
Sponsor:
Dokuz Eylul University
Organization:
Dokuz Eylul University
Study Overview
Official Title:
The Effect of Maximal Exercise on Matrix Metalloproteinase Enzyme and Its Inhibitor MMP9 and TIMP1 and The Role of MMP9 -1562 CT and TIMP1 372 TC Polymorphisms
Status:
COMPLETED
Status Verified Date:
2020-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Matrix metalloproteinases MMPs play a critical role in the remodeling and regeneration of skeletal muscle Studies which investigate exercise and effects of MMPs and tissue inhibitors of matrix metalloproteinases TIMPs are contradictory Also the role of MMP9 -1562 CT and TIMP1 372 TC polymorphisms on exercise are unclear In accordance with this conditions the hypothesis of the study are as follows
1 Levels of basal serum MMP9 and TIMP1 are different between athletes volleyball basketball handball and sedentary people
2 Levels of serum MMP9 and TIMP1 response to maximal exercise are different between athletes volleyball basketball handball and sedentary people
3 Relationship between levels of serum MMP9 and TIMP1 response to maximal exercise are different between athletes volleyball basketball handball and sedentary people
4 Levels of basal serum MMP9 and TIMP1 are related to MMP9 -1562 CT and TIMP1 372 TC polymorphisms
5 Relationship between levels of serum MMP9 and TIMP1 response to maximal exercise and MMP9 -1562 CT and TIMP1 372 TC polymorphisms are different between athletes volleyball basketball handball and sedentary people
1 Levels of basal serum MMP9 and TIMP1 are different between athletes volleyball basketball handball and sedentary people
2 Levels of serum MMP9 and TIMP1 response to maximal exercise are different between athletes volleyball basketball handball and sedentary people
3 Relationship between levels of serum MMP9 and TIMP1 response to maximal exercise are different between athletes volleyball basketball handball and sedentary people
4 Levels of basal serum MMP9 and TIMP1 are related to MMP9 -1562 CT and TIMP1 372 TC polymorphisms
5 Relationship between levels of serum MMP9 and TIMP1 response to maximal exercise and MMP9 -1562 CT and TIMP1 372 TC polymorphisms are different between athletes volleyball basketball handball and sedentary people
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None