Ignite Creation Date:
2024-05-06 @ 1:53 PM
Last Modification Date:
2024-10-26 @ 1:21 PM
Study NCT ID:
NCT04151173
Status:
UNKNOWN
Last Update Posted:
2021-06-11
First Post:
2019-10-30
Brief Title:
Assessment of Ovarian Reserve After Laparoscopic Cystectomy Versus AspirationElectrocoagulation in the Treatment of Ovarian Endometrioma
Sponsor:
Shanghai First Maternity and Infant Hospital
Organization:
Shanghai First Maternity and Infant Hospital
Study Overview
Official Title:
Assessment of Ovarian Reserve After Laparoscopic Cystectomy Versus AspirationElectrocoagulation in the Treatment of Ovarian Endometrioma
Status:
UNKNOWN
Status Verified Date:
2021-06
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a prospective multicentric three centers 1 Shanghai First Maternity and Infant Hospital Shanghai China 2 International Peace Maternity and Child Health Hospital Shanghai China 3 Shanghai Tongji Hospital Tongji University School of Medicine Shanghai China randomized clinical trial that includes patients undergoing laparoscopic surgery for primary unilateral ovarian endometriomas Eligible patients will be subjected to transvaginal ultrasound before surgery to perform cyst classification central type marginal type and outcrop type Patients are divided to two group laparoscopic cystectomy group versus laparoscopic aspirationelectrocoagulation group Biopsy samples in aspirationelectrocoagulation group and excision samples in cystectomy group are all subjected to histopathological examination Follicular stimulating hormone FSH Anti mullerian hormone AMH and antral follicular count AFC will be measured pre-operative and post-operative
The aim of the study is to determine whether and to what extent the two surgical procedures for ovarian endometrioma cystectomy and aspirationelectrocoagulation affect ovarian reserve The investigators intend to confirm the clinical utility of ultrasonic classification of ovarian endometrioma FSH AMH and AFC in the assessment of ovarian reserve and to promote their use in predicting decreased ovarian reserve
The surgical excision of cystic wall cystic fluid and peritoneal fluid will be subjected to transmission electron microscope high resolution mass spectrometry and single-cell RNA sequencing to investigate their cellular and molecular features
The aim of the study is to determine whether and to what extent the two surgical procedures for ovarian endometrioma cystectomy and aspirationelectrocoagulation affect ovarian reserve The investigators intend to confirm the clinical utility of ultrasonic classification of ovarian endometrioma FSH AMH and AFC in the assessment of ovarian reserve and to promote their use in predicting decreased ovarian reserve
The surgical excision of cystic wall cystic fluid and peritoneal fluid will be subjected to transmission electron microscope high resolution mass spectrometry and single-cell RNA sequencing to investigate their cellular and molecular features
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None