Viewing Study NCT00363597



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Study NCT ID: NCT00363597
Status: COMPLETED
Last Update Posted: 2020-12-19
First Post: 2006-08-11

Brief Title: Intestinal Permeability in ChildrenAdolescents With Functional Dyspepsia
Sponsor: Childrens Mercy Hospital Kansas City
Organization: Childrens Mercy Hospital Kansas City

Study Overview

Official Title: Intestinal Permeability and Serum Zonulin Concentration in ChildrenAdolescents With Functional Dyspepsia
Status: COMPLETED
Status Verified Date: 2020-12
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: The main purpose of this study is to evaluate whether intestinal permeability andor serum zonulin concentration is increased in childrenadolescents with functional dyspepsia FD The study will also explore the relationships between intestinal permeability mucosal inflammation and anxiety in FD patients
Detailed Description: Recurrent abdominal pain is a common complaint among school-age children being present in up to 15 at any given time It represents the most common chronic pain entity in pediatric patients The great majority of these patients will have a functional gastrointestinal disorder FGID The most common FGID in these patients is functional dyspepsia FD defined as upper abdominal pain or discomfort unrelieved by bowel movement and in the absence of a structural or biochemical explanation for the pain The etiology of FD is multifactorial including biological factors and these factors can be viewed within a biopsychosocial model Biological factors include inflammation dysmotility and increased visceral sensitivity These biological factors are influenced by and are interactive with psychosocial factors such as anxiety depression and social interaction This study will evaluate intestinal permeability as a measure of barrier dysfunction and investigate the correlations between increased permeability mucosal inflammation and anxiety scores to provide further insight into the etiology of FD thereby assisting in the development and selection of treatment modalities

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None