Ignite Creation Date:
2024-05-06 @ 1:50 PM
Last Modification Date:
2024-10-26 @ 1:20 PM
Study NCT ID:
NCT04133805
Status:
UNKNOWN
Last Update Posted:
2019-10-21
First Post:
2019-06-24
Brief Title:
The Effect of Viscous Dietary Fibers on LDL-cholesterol
Sponsor:
Unity Health Toronto
Organization:
Unity Health Toronto
Study Overview
Official Title:
The Effect of Viscous Dietary Fibers on LDL-cholesterol A Systematic Review and Meta-analysis of Randomized Controlled Trials
Status:
UNKNOWN
Status Verified Date:
2019-10
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This systematic review and meta-analysis is aimed to assess the effect of commonly consumed viscous fibers on blood lipids including LDL-C non-HDL-C and ApoB
Detailed Description:
Medline Embase CINAHL and the Cochrane Central databases were searched through May 13 2019 Three independent reviews extracted data and assessed risk of bias Randomized controlled trials that assessed the effect of barley b-glucan oat b-glucan konjac glucomannan KJM psyllium guar gum and pectin with a study duration of 3 weeks in adults with or without hypercholesterolemia were included Data were pooled using the generic inverse variance method with random effects models and expressed as mean differences with 95 confidence intervals Heterogeneity was assessed by the Cochran Q statistic and quantified by I2 statistic Overall quality of the evidence was assessed using the GRADE Grading of Recommendations Assessment Development and Evaluation approach
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None