Ignite Creation Date:
2024-05-06 @ 1:48 PM
Last Modification Date:
2024-10-26 @ 1:20 PM
Study NCT ID:
NCT04131894
Status:
COMPLETED
Last Update Posted:
2019-10-18
First Post:
2019-10-15
Brief Title:
Effects of Autogenous Dentin Graft on Socket Preservation
Sponsor:
Bahçeşehir University
Organization:
Bahçeşehir University
Study Overview
Official Title:
Healing of Extraction Sockets Preserved With Autogenous Dentin Graft A Clinical Histological Histomorphometrical and Electron Microscobic Study
Status:
COMPLETED
Status Verified Date:
2019-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Various graft materials are used to reconstruct bone defects in the jaws due to tooth loss trauma advanced periodontal diseases pathological lesions and congenital disorders The main features of an ideal bone graft are osteogenesis osteoinduction and osteoconduction Autogenous bone graft is considered as the gold standard among all bone graft materials Because it has all the features that an ideal bone graft should have However there are some disadvantages such as donor site morbidity obtaining limited amounts and high rates of resorption Because of these disadvantages other bone graft materials such as allografts xenografts and alloplastic bone grafts are frequently used for bone augmentation In the light of recent studies the limits of conventional bone graft materials such as limited osteoconduction capacity and disease transmission have been clearly demonstrated Due to the disadvantages of these materials studies are directed to develop alternative graft materials Aim of this study is to analyse the effects of autogenous dentin graft and mixture of autogenous dentin graft and platelet rich fibrin PRF applied to the tooth extraction sockets on bone healing process A total of 57 extraction sockets in 9 patients who were planned to be treated with dental implant after tooth extraction were evaluated in this study Extraction sockets were divided randomly into 3 groups In the first group sockets were filled with autogenous dentin graft Group D-20 sockets In the second group sockets were filled with the mixture of PRF and autogenous dentin graft Group DP-21 sockets In the third group sockets were left empty as control group Group C-16 sockets After 3 months histological and immunohistochemical evaluations were performed on the samples taken during the implant surgery Additionally samples obtained from each group were examined by scanning electron microscopy SEM
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None