Ignite Creation Date:
2024-05-06 @ 1:48 PM
Last Modification Date:
2024-10-26 @ 1:19 PM
Study NCT ID:
NCT04121273
Status:
UNKNOWN
Last Update Posted:
2021-03-03
First Post:
2019-10-08
Brief Title:
GPC3-targeted CAR-T Cell for Treating GPC3 Positive Advanced HCC
Sponsor:
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Organization:
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Study Overview
Official Title:
Clinical Study of GPC3-targeted Chimeric Antigen Receptor T Cells fo Treating Advanced Hepatocellular Carcinoma
Status:
UNKNOWN
Status Verified Date:
2021-03
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Patients with hepatocellular carcinoma a type of primary liver cancers are enrolls in this study The cancer has progressed after standard treatment or the patient cannot receive regular treatment
Investigator made a gene called chimeric antigen receptor derived from an antibody that recognizes Glypican 3 a protein detected in in a large proportion of hepatocellular carcinoma The gene will introduce into T cell from patients blood to make them recognize and kill cancer cells
The aim of this study is to evaluate the efficacy tolerance and safety of chimeric antigen receptor-modified T CAR-T cell targeting Glypican 3 for advanced hepatocellular carcinoma
Investigator made a gene called chimeric antigen receptor derived from an antibody that recognizes Glypican 3 a protein detected in in a large proportion of hepatocellular carcinoma The gene will introduce into T cell from patients blood to make them recognize and kill cancer cells
The aim of this study is to evaluate the efficacy tolerance and safety of chimeric antigen receptor-modified T CAR-T cell targeting Glypican 3 for advanced hepatocellular carcinoma
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None