Ignite Creation Date:
2024-05-06 @ 1:46 PM
Last Modification Date:
2024-10-26 @ 1:20 PM
Study NCT ID:
NCT04126577
Status:
COMPLETED
Last Update Posted:
2023-08-29
First Post:
2019-10-11
Brief Title:
Clinical Relevance of the Reverse Lipopolysaccharide Transport Pathway in Patients With Acute Peritonitis
Sponsor:
Centre Hospitalier Universitaire Dijon
Organization:
Centre Hospitalier Universitaire Dijon
Study Overview
Official Title:
Clinical Relevance of the Reverse Lipopolysaccharide Transport Pathway in Patients With Acute Peritonitis An Observational Prospective Study
Status:
COMPLETED
Status Verified Date:
2023-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
LIPS
Brief Summary:
When there is infection in the intra-abdominal area bacteria secrete toxins that are absorbed by the peritoneum These toxins then bind to lipoproteins which carry cholesterol in the blood and are eliminated by the liver Phospholipid transfer protein PLTP is a protein that facilitates the binding of bacterial toxins to lipoproteins and thus their elimination
The objective of this study is to study the relationship between PLTP and the elimination of bacterial toxins in humans A better understanding of the elimination of these toxins will lead to a better understanding of the disease The ultimate objective is to improve the management of intra-abdominal infections
The objective of this study is to study the relationship between PLTP and the elimination of bacterial toxins in humans A better understanding of the elimination of these toxins will lead to a better understanding of the disease The ultimate objective is to improve the management of intra-abdominal infections
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None