Ignite Creation Date:
2024-05-06 @ 1:43 PM
Last Modification Date:
2024-10-26 @ 1:18 PM
Study NCT ID:
NCT04103294
Status:
COMPLETED
Last Update Posted:
2019-09-25
First Post:
2019-06-12
Brief Title:
Measuring Cowpea Consumption in Young Children and Pregnant Women in Ghana
Sponsor:
Washington University School of Medicine
Organization:
Washington University School of Medicine
Study Overview
Official Title:
Measuring Cowpea Consumption in Young Children and Pregnant Women in Ghana
Status:
COMPLETED
Status Verified Date:
2019-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Current dietary assessment methods rely on self-report food intake such as food frequency questionnaires 24-hr dietary recall or diet diaries and the prevalence of misreporting with these tools is estimated at 30-88A reliable and convenient way to measure the quantity of cowpea consumed by an individual The hope is to identify a novel set of dietary biomarkers that will measure cowpea consumption be free from participant recall bias and serve to quantify legume intake A total of 40 subjects 20 children 9-21 months and 20 pregnant women 18 yr will consume 3 distinct daily intake dosages of cooked cowpeas with the daily intake increased every 5 days Urine samples will be collected 3 times during each 5-day period and blood spots will be collected during a washout period and at the end of the final 5-day period Urine samples will undergo metabolite detection via ultra-performance liquid chromatography tandem mass spectrometry in positive and negative ion mode Peaks are quantified using area-under-the-curve AUC and each metabolite is quantified in terms of its median-scaled relative abundance for the metabolite across the entire data set A repeated measures 2-way ANOVA will be used to compare cowpea metabolite abundances over time and with respect to variation in an individual baseline levels
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None