Ignite Creation Date:
2024-05-05 @ 4:59 PM
Last Modification Date:
2024-10-26 @ 9:27 AM
Study NCT ID:
NCT00366912
Status:
TERMINATED
Last Update Posted:
2009-08-11
First Post:
2006-08-18
Brief Title:
Unloading Respiratory Muscles During NIV Comparison of a Spontaneous and Auto-adjusting Controlled Mode
Sponsor:
Krankenhaus Kloster Grafschaft
Organization:
Krankenhaus Kloster Grafschaft
Study Overview
Official Title:
None
Status:
TERMINATED
Status Verified Date:
2009-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
No longer recruiting participants are no longer being recruited or enrolled
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Measurement of Work of breathing WOB as well as pressure time product PTP of transdiaphragmatic pressures to evaluate the degree of muscle activity and muscle unloading during non-invasive ventilation
The study makes comparison of a new developed auto adjusting controlled mode and a regular spontaneous mode
The study makes comparison of a new developed auto adjusting controlled mode and a regular spontaneous mode
Detailed Description:
Non-invasive ventilation NIV reduces carbon dioxide in hypercapnic respiratory failure by unloading the respiratory muscles Spontaneous modes of NIV are usually being used in these situations Spontaneous modes have the disadvantage that the patient has to trigger the ventilator The work to activate the trigger WT is estimated to be as high as up to 50 of the total work of breathing dependent on the underlying disease Elimination of WT would increase the degree of respiratory muscle unloading
A new pressure controlled mode incorporated into the ventilogic mechanical ventilator Weinmann Germany is capable of self adjusting respiratory parameters in a preset range according to the patient requirements
After a short period where the patients spontaneous respiratory parameters are being analyzed the ventilator slowly implements a pressure controlled mode that matches the patients requirements
This study intends to investigate if this new mode achieves a higher degree of respiratory muscle unloading compared to a spontaneous mode
A new pressure controlled mode incorporated into the ventilogic mechanical ventilator Weinmann Germany is capable of self adjusting respiratory parameters in a preset range according to the patient requirements
After a short period where the patients spontaneous respiratory parameters are being analyzed the ventilator slowly implements a pressure controlled mode that matches the patients requirements
This study intends to investigate if this new mode achieves a higher degree of respiratory muscle unloading compared to a spontaneous mode
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None