Viewing Study NCT00364962



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Study NCT ID: NCT00364962
Status: UNKNOWN
Last Update Posted: 2006-08-16
First Post: 2006-08-15

Brief Title: Treatment Result of KTP Laser Nasopharyngectomy in Recurrent NPC Patients
Sponsor: National Taiwan University Hospital
Organization: National Taiwan University Hospital

Study Overview

Official Title: None
Status: UNKNOWN
Status Verified Date: 2006-08
Last Known Status: RECRUITING
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Investigate the treatment result of KTP laser nasopharyngectomy in recurrent NPC patients
Detailed Description: Nasopharyngeal carcinomas NPCs are highly radiosensitive tumors and the primary treatment of NPCs is radiotherapy1 Because most patients who have NPC are at advanced stages when initially seen local failures in terms of persistence or recurrence are not infrequent after primary radiotherapy23 Local regional relapse without the presence of distant failure can still be salvaged and should be aggressively treated Tumors relapsing in the nasopharynx can be salvaged using either re-irradiation or surgical techniques1 Although re-irradiation to the recurrent tumor can extent the 5-year actuarial survival rate it is associated with high morbidity 4-6 Traditional nasopharyngectomy has been associated with local control rates on the order of 4050 but it has also been associated with complications such as palatal defects trismus facial scarring osteomyelitis etc7-10 That is the reason why surgeons continue searching for new methods for performing nasopharyngectomies with lower morbidities

Nasopharyngectomies are difficult to perform because of the inaccessibility of the nasopharynx More difficulties are encountered in performing a nasopharyngectomy through the nose due to the restricted surgical field With advances in techniques of endoscopy and application of the potassium-titanyl-phosphate KTP laser in surgery pathologic lesions located either at the choanal margin or in the nasopharynx can easily be managed with instruments inserted via the nasal cavities The surgical technique had been accepted by the authority journal This time we will review the therapeutic result of KTP-laser nasopharyngectomy in patients with recurrent NPC

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None