Ignite Creation Date:
2024-05-05 @ 4:59 PM
Last Modification Date:
2024-10-26 @ 9:27 AM
Study NCT ID:
NCT00369044
Status:
SUSPENDED
Last Update Posted:
2009-04-08
First Post:
2006-08-28
Brief Title:
Prednisone for Decompensated Congestive Heart Failure
Sponsor:
Hebei Medical University
Organization:
Hebei Medical University
Study Overview
Official Title:
Chronic Administration of Prednisone in Management of Patients With Decompensated Congestive Heart Failure
Status:
SUSPENDED
Status Verified Date:
2007-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
We designed this randomized double-blind placebo-controlled trial to determine the clinical efficacy of chronic administration of prednisone on renal function and clinical status when added to standard care
Detailed Description:
Studies showed that glucocorticoids could specifically dilate renal vessel increase in GFR and regulate synthesis and release of atrial natriuretic peptide ANP upregulate ANP receptors on vascular endothelial cells leading to significant diuresis and natriuresis Adding glucocorticoids to standard care may potentiate the diuretic and natriuretic effects of diuretics and improve renal function thus improve the clinical outcomes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None