Viewing Study NCT04073277



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Last Modification Date: 2024-10-26 @ 1:17 PM
Study NCT ID: NCT04073277
Status: COMPLETED
Last Update Posted: 2019-08-29
First Post: 2019-08-26

Brief Title: Acupuncture Needle Modified With Supercritical Fluid
Sponsor: Chang Gung Memorial Hospital
Organization: Chang Gung Memorial Hospital

Study Overview

Official Title: Study on Improving Acupuncture Needles and Physical Properties of Acupoints With Supercritical Fluid
Status: COMPLETED
Status Verified Date: 2018-07
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Objective To compare the differences in the needling sensation with acupuncture needles surface treated with nitrogen applied supercritical fluid SCF-N and stainless steel needles

Materials and Methods This was a double-blind prospective cohort study The acupuncture needles were randomly used in this experiment including the SCF-N-treated needles and the control stainless steel needles LI 4 Hegu and LI 11 Quchi acupuncture points in the Yangming Large Intestine Meridian of Hand were treated Physical electrical resistance scanning electron microscopy energy dispersive spectrometry and visual analog scale score including the sensations of soreness numbness distention and heaviness were assessed
Detailed Description: This was a double-blinded prospective cohort study The acupuncture needles were first separated into two groups One group of needles was subjected to SCF-N treatment while the other was not The needles were then randomly analyzed with scanning electron microscope and energy dispersive X-ray spectroscopy to ensure quality and minimize experimental error For each participant one hand was randomly assigned to the treatment group with SCF-N-treated acupuncture needles and the other hand was assigned to the control group with the stainless steel needles The time interval between the acupuncture treatment of the two groups was about two hours In order to examine and distinguish the difference between the two groups de-qi VAS score was recorded by the volunteers during needle insertion and the electrical resistance by electrical measurement

The acupuncture needles used in this experiment including the SCF-N-treated needles and the control stainless steel needles were produced under the same conditions in the same factory Dong Bang acupuncture Inc and on the same day to minimize experimental error

The process of SCF treatment First the stainless steel chamber and quartz carrier were sterilized using alcohol and autoclaving Next the needles were placed on the quartz carrier with the tip pointing upwards and then placed in the chamber and covered Carbon dioxide was used to remove atmospheric components from the chamber and required volume of ammonia gas was passed The pressure was increased up to 3000 pound per square inchpsi and temperature up to 120 An hour later the pressure was relieved and the process of SCF treatment completed After completion of the treatment the needles were then randomly selected for material analysis and electrical measurement Following this the needles were stored in a vacuum bag This was done to reduce the influence of atmospheric contaminants on the needles after treatment resulting in oxidation and rusting Finally there would be heterogeneous contact between the inorganic metal and the acupuncture needle Hence nitrogen was selected as the main agent for SCF treatment

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None