Ignite Creation Date:
2024-05-06 @ 1:35 PM
Last Modification Date:
2024-10-26 @ 1:16 PM
Study NCT ID:
NCT04066101
Status:
COMPLETED
Last Update Posted:
2021-04-15
First Post:
2019-08-21
Brief Title:
TAS1R1 TAS1R3 TLR2 TLR4 CA6 Gene Polymorphism on Dental Caries
Sponsor:
Recep Tayyip Erdogan University Training and Research Hospital
Organization:
Recep Tayyip Erdogan University Training and Research Hospital
Study Overview
Official Title:
Variants in Taste Genes on Caries Risk and Caries Activity Status
Status:
COMPLETED
Status Verified Date:
2021-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to examine the effects of TAS1R1 TAS1R3 TLR2 TLR4 CA6 gene polymorphism on caries risk in adults
Detailed Description:
To date genes can be grouped into categories based on the factor influencing dental caries The major candidate gene categories to date include enamel formation genes immune response genes genes related to saliva and genes related to taste and dietary habits
CA6 exists in the human saliva and has a critical role of buffering immune response and tasteToll-like receptors are expressed in the tongue gustatory papillae where they may initiate immune responses to pathogensGenetic variations in the TAS1R1 and TAS1R3 for umami cause perception of these tastes differently
CA6 exists in the human saliva and has a critical role of buffering immune response and tasteToll-like receptors are expressed in the tongue gustatory papillae where they may initiate immune responses to pathogensGenetic variations in the TAS1R1 and TAS1R3 for umami cause perception of these tastes differently
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None