Ignite Creation Date:
2024-05-05 @ 4:58 PM
Last Modification Date:
2024-10-26 @ 9:26 AM
Study NCT ID:
NCT00358137
Status:
COMPLETED
Last Update Posted:
2016-02-18
First Post:
2006-07-28
Brief Title:
Effect of Aerobic Exercise on Blood Pressure Changes
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
Psychophysiologic Stress Exercise Autonomic Control
Status:
COMPLETED
Status Verified Date:
2007-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will evaluate the effect of an aerobic training program versus a strength training program on the autonomic nervous system at rest and in response to challenge
Detailed Description:
The purpose of this study is to compare the effectiveness of an aerobic exercise program versus a strength training program in altering RR interval and blood pressure variability as indices of autonomic nervous system regulation of the cardiovascular system Subjects will be tested at rest and in response to challenge
This study will enroll healthy young age 18-45 sedentary individuals at Columbia University Medical Center and St Johns University At an initial screening visit potential participants will be screened for exercise activity and will also undergo a test of aerobic capacity Subjects will be eligible if they are not exercising regularly and do not exceed American Heart Association standards for average fitness VO2max 43 and 37 mlkgmin for men and women respectively Exclusion criteria include current symptoms of affective disorder psychosis or substance abuse current usage of psychotropic medication and any medical condition that affected the autonomic nervous system or cardiovascular system
Eligible participants will then be randomly assigned to 12 weeks of either an aerobic conditioning program or a strength training program At study entry heart rate respiratory rate and blood pressure will be measured an ECG will be used to measure heart activity Questionnaires will be completed to assess anger tension depression and fatigue Participants in the aerobic conditioning program will attend four 1-hour exercise sessions per week which will focus on increasing cardiovascular fitness through running and other forms of aerobic exercise The strength training program will also include four sessions per week with the focus on increasing muscle endurance and strength At the end of the 12-week programs participants will begin a 4-week period of deconditioning during which they will discontinue all exercise Evaluations will be repeated at the end of the 12-week programs and at the end of the 4-week deconditioning period
This study will enroll healthy young age 18-45 sedentary individuals at Columbia University Medical Center and St Johns University At an initial screening visit potential participants will be screened for exercise activity and will also undergo a test of aerobic capacity Subjects will be eligible if they are not exercising regularly and do not exceed American Heart Association standards for average fitness VO2max 43 and 37 mlkgmin for men and women respectively Exclusion criteria include current symptoms of affective disorder psychosis or substance abuse current usage of psychotropic medication and any medical condition that affected the autonomic nervous system or cardiovascular system
Eligible participants will then be randomly assigned to 12 weeks of either an aerobic conditioning program or a strength training program At study entry heart rate respiratory rate and blood pressure will be measured an ECG will be used to measure heart activity Questionnaires will be completed to assess anger tension depression and fatigue Participants in the aerobic conditioning program will attend four 1-hour exercise sessions per week which will focus on increasing cardiovascular fitness through running and other forms of aerobic exercise The strength training program will also include four sessions per week with the focus on increasing muscle endurance and strength At the end of the 12-week programs participants will begin a 4-week period of deconditioning during which they will discontinue all exercise Evaluations will be repeated at the end of the 12-week programs and at the end of the 4-week deconditioning period
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL061287-04 | NIH | None | httpsreporternihgovquickSearchR01HL061287-04 |