Ignite Creation Date:
2024-05-05 @ 4:57 PM
Last Modification Date:
2024-10-26 @ 9:26 AM
Study NCT ID:
NCT00350025
Status:
COMPLETED
Last Update Posted:
2017-03-31
First Post:
2006-07-07
Brief Title:
Study of Cetuximab With and Without Weekly Paclitaxel for Patients With Previously Treated Advanced Urothelial Cancer
Sponsor:
Fox Chase Cancer Center
Organization:
Fox Chase Cancer Center
Study Overview
Official Title:
Randomized Phase II Trial of Cetuximab With and Without Weekly Paclitaxel in Patients With Previously Treated Advanced Urothelial Cancer
Status:
COMPLETED
Status Verified Date:
2017-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this research study is to determine whether the investigational drug cetuximab Erbitux alone or with paclitaxel Taxol can stabilize the growth of urothelial cancer
Detailed Description:
This research study is being done to find out if cetuximab alone or with paclitaxel will slow the growth of urothelial cancers Cetuximab is an antibody that blocks a protein called epidermal growth factor receptor EGFR EGFR sits on the outside of tumor cells and controls tumor cell growth This agent has been looked at alone and with other chemotherapy drugs including paclitaxel It has been found to be safe and can shrink other types of cancer
This research study is also being done to find out if cetuximab alone or with paclitaxel shrinks urothelial tumors If it extends the time the tumors shrink If it helps people live longer
The purpose of this research study is to find out what effects good and bad these treatments have on you and your cancer We do not know if you will benefit from this research study It is possible that your condition will get better but it is also possible that there will be no effect on your condition or that your condition will get worse We can use what we learn from this research study to help other people with the same disease
This research study is also being done to find out if cetuximab alone or with paclitaxel shrinks urothelial tumors If it extends the time the tumors shrink If it helps people live longer
The purpose of this research study is to find out what effects good and bad these treatments have on you and your cancer We do not know if you will benefit from this research study It is possible that your condition will get better but it is also possible that there will be no effect on your condition or that your condition will get worse We can use what we learn from this research study to help other people with the same disease
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None