Ignite Creation Date:
2024-05-05 @ 4:57 PM
Last Modification Date:
2024-10-26 @ 9:26 AM
Study NCT ID:
NCT00358839
Status:
COMPLETED
Last Update Posted:
2006-11-10
First Post:
2006-07-31
Brief Title:
Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2
Sponsor:
Danish Headache Center
Organization:
Danish Headache Center
Study Overview
Official Title:
Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2
Status:
COMPLETED
Status Verified Date:
2006-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of the present study is to explore functional consequences of migraine gene mutations on their responses to Calcitonin Gene Related Peptide CGRPinfusion
Detailed Description:
Calcitonin Gene Related Peptide CGRP induces migraine attacks indistinguishable from spontaneous attacks in approximately 50 of migraine sufferers Treatment of spontaneous migraine attacks with an antagonist to CGRP is effective in many patients These data show that CGRP is involved in both initiation and maintenance of migraine attack
The consequence of migraine gene mutations on relevant migraine pathways has never been tested The aim of the present study is to explore functional consequences of migraine gene mutations on their responses to CGRP infusion The project will improve our understanding of the neurobiology of migraine and stimulate development of new treatment targets
The consequence of migraine gene mutations on relevant migraine pathways has never been tested The aim of the present study is to explore functional consequences of migraine gene mutations on their responses to CGRP infusion The project will improve our understanding of the neurobiology of migraine and stimulate development of new treatment targets
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None