Ignite Creation Date:
2024-05-06 @ 1:26 PM
Last Modification Date:
2024-10-26 @ 1:14 PM
Study NCT ID:
NCT04022837
Status:
UNKNOWN
Last Update Posted:
2019-07-17
First Post:
2019-07-03
Brief Title:
Effect of Proton Pump Inhibitor of Daily Use for One Month on Kidney Function Test
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Effect of Proton Pump Inhibitor of Daily Use for One Month on Kidney Function Test
Status:
UNKNOWN
Status Verified Date:
2019-07
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study to
evaluate the association between prolonged use of PPI and adverse renal outcomes on patients with normal renal function and others with abnormal renal function
evaluate the association between prolonged use of PPI and adverse renal outcomes on patients with normal renal function and others with abnormal renal function
Detailed Description:
Proton pump inhibitors PPIs are one of the most widely used classes of drugs and are prescribed primarily for gastric acid-related diseases eradication of Helicobacter pylori and prevention of nonsteroidal anti-inflammatory drug NSAID-induced gastropathyand gastroesophagial reflux diseases Although PPIs have an excellent overall safety profile some severe adverse effects which include bone fracture dementia myocardial infarction infections micronutrient deficiencies and kidney diseases PPIs may trigger acute interstitial nephritisa potentially sever adverse event commonly associated with acute kidney injury The increase in prescription and inadequate use of this class of medication calls for studies on the effects of prolonged PPI therapy on renal function
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None