Ignite Creation Date:
2024-05-06 @ 1:25 PM
Last Modification Date:
2024-10-26 @ 1:13 PM
Study NCT ID:
NCT04010175
Status:
TERMINATED
Last Update Posted:
2022-03-04
First Post:
2019-07-03
Brief Title:
Digital Cognitive Remote Training in Alzheimers Disease MA-EIAD
Sponsor:
Hospices Civils de Lyon
Organization:
Hospices Civils de Lyon
Study Overview
Official Title:
Cognitive Training in Early to Moderate Stages Alzheimers Disease Patients Contribution of Digital Remote Training
Status:
TERMINATED
Status Verified Date:
2022-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Recruitment stopped for thesis defense It was not possible to extend the period of inclusion to achieve the patient objective
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
DCRT-AD
Brief Summary:
Cerebral functioning changes with age in order to respond to the impacts of different external and internal factors on the brain and more generally on the human body Scaffolding Theory of Aging and Cognition proposes that during life the brain develops specific neural networks to handle with cognitive activities When these networks are impaired due to factors that damage brain structure andor brain functioning the brain adapts and elaborates new networks to cope with this situation A cognitive reserve built throughout life and an appropriated care such as for example cognitive training are in the centre of this model because they are involved in building these networks In general studies exploring cognitive training in normal aging and in patients suffering from neurodegenerative disease such as Alzheimers disease have shown some benefits of the training on cognitive functioning It has been shown not only that the cognitive training improves older adults cognition but also that these effects last for a long time and positively influence older people everyday activities In fact the benefits from memory training were observed 5 years after the end of the training and those of reasoning and of speed of processing even after 10 years In addition majority of the participants declared to notice improvement of their everyday life Concerning Alzheimers disease several studies have observed positive results of cognitive training although there are some controversies about its effects Numerous studies point out that for cognitive training being the most efficient the intervention has to take place as early as possible preferentially in a premorbid stage of the disease and that it is important to propose trainings that minimize the withdrawal In this sense the importance of using computer based training was put forward because it allows the elaboration of multiple exercises with playful aspect and more importantly it can adapt on line the difficulty of the exercises to the patients performance However if it is commonly admitted that computer based training has an important role in physicians psychologists or speech therapists office less is known about the efficiency of this type of training performed at distance at the patients place of residence It seems probable that to propose distance training as an additional training to that performed in a practitioners office would increase training benefits To investigators knowledge this was not investigated in a systematic way with Alzheimers disease patients The more important advantages of a such additional training are 1 reduction of patients travelling 2 increased flexibility of training scheduling and 3 increased frequency of training sessions per week
Thus in the present study investigators will examine in a systematic way whether the distance training as an additional training to this performed in practitioners office brings incremental short- and long-term benefits coming from cognitive training in mild to moderate Alzheimers disease patients Investigators second objective is to determine what would be the best frequency per week of such an additional training
Thus in the present study investigators will examine in a systematic way whether the distance training as an additional training to this performed in practitioners office brings incremental short- and long-term benefits coming from cognitive training in mild to moderate Alzheimers disease patients Investigators second objective is to determine what would be the best frequency per week of such an additional training
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None