Ignite Creation Date:
2024-05-06 @ 1:25 PM
Last Modification Date:
2024-10-26 @ 1:13 PM
Study NCT ID:
NCT04016350
Status:
COMPLETED
Last Update Posted:
2019-07-11
First Post:
2019-07-05
Brief Title:
Impact of Exercise Combined With Inulin Propionate Ester on Fat Oxidation
Sponsor:
University of Glasgow
Organization:
University of Glasgow
Study Overview
Official Title:
Impact of Moderate Intensity Exercise Training Combined With Inulin Propionate Ester Supplementation on Whole Body Resting Fat Oxidation and Body Weigh in Overweight Women
Status:
COMPLETED
Status Verified Date:
2019-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
IPE
Brief Summary:
There is evidence to suggest that responsiveness to exercise training programmes can be expected to be influenced by changes in resting fat oxidation an important factor in the aetiology of obesity Our previous work has shown that oral supplementation with inulin propionate ester IPE reduces intra-abdominal fat and prevents weight gain and that oral propionate intake enhances resting fat oxidation The effects of IPE combined with exercise training on resting fat oxidation and body fatness are unknown The aim of this study was to investigate the impact of 4-weeks IPE supplementation in combination with a moderate intensity exercise training programme on whole body fat oxidation and on plasma GLP-1 and PYY
Detailed Description:
Participants Healthy overweight females with BMI 25 kgm2 and 25-45 years of age were recruited through advertisements and word of mouth on the campus of the University of Glasgow or from other public places Participants were required to be sedentary non-smokers with stable body weight for two months prior to the study enrollment not pregnant free of medication nutritional supplementation or following any specific diet and with no antibiotic use for the past three months Participants with chronic illness eating disorders and history of gastrointestinal operations were excluded
Study Design This is a randomized study with a parallel design Study participants underwent 4 week supervised moderate intensity exercise training combined either with IPE EXIPE or cellulose as placebo EXPlacebo supplementation at doses of 10g day Supplements were provided as sachets containing white powder and participants were asked to consume one sachet per day with breakfast in a way convenient for each participant Before the start of the study and at the end of the 4-week intervention participants were asked to conduct a submaximal exercise test Prior to the first and after the second submaximal exercise test participants of both groups conducted a 7-hour experimental trial which involved collection of expired air and blood samples in fasted and postprandial states Body weight and body composition were measured in the fasted state Prior to the first 7-hour experimental trial participants were asked to record their diet for 3 days and replicate this intake prior to the second 7-hour experimental trial
Study Design This is a randomized study with a parallel design Study participants underwent 4 week supervised moderate intensity exercise training combined either with IPE EXIPE or cellulose as placebo EXPlacebo supplementation at doses of 10g day Supplements were provided as sachets containing white powder and participants were asked to consume one sachet per day with breakfast in a way convenient for each participant Before the start of the study and at the end of the 4-week intervention participants were asked to conduct a submaximal exercise test Prior to the first and after the second submaximal exercise test participants of both groups conducted a 7-hour experimental trial which involved collection of expired air and blood samples in fasted and postprandial states Body weight and body composition were measured in the fasted state Prior to the first 7-hour experimental trial participants were asked to record their diet for 3 days and replicate this intake prior to the second 7-hour experimental trial
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| BBL0042591 | OTHER_GRANT | BBSRC | None |