Ignite Creation Date:
2024-05-06 @ 1:19 PM
Last Modification Date:
2024-10-26 @ 1:12 PM
Study NCT ID:
NCT03984994
Status:
COMPLETED
Last Update Posted:
2024-01-24
First Post:
2019-06-05
Brief Title:
Muscle Capillarization and Sarcopenia
Sponsor:
Baltimore VA Medical Center
Organization:
Baltimore VA Medical Center
Study Overview
Official Title:
Increasing Muscle Capillarization to Enhance Responses to Strength Training in Sarcopenia
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Aging is associated with a loss of muscle mass termed sarcopenia that reduces mobility decreases physical function and accelerates progression of other age-related disorders This study is designed to determine whether increasing skeletal muscle capillarization through aerobic exercise will enhance muscular adaptations to strength training in older adults with sarcopenia
Detailed Description:
Sarcopenia or the aging-related loss of muscle mass affects a large number of older adults The presence of sarcopenia is associated with physical disability poor quality of life and all-cause mortality in part because sarcopenic adults have low muscle skeletal muscle capillarization and may lack the adequate perfusion needed to maintain muscle mass and function This study will test the effects of increasing skeletal muscle capillarization through aerobic exercise training on responses to resistance training in older adults Eligible participants will be randomized to one of two groups resistance training preceded by aerobic exercise training AEX-RT or resistance training followed by aerobic exercise training RT-AEX Participants in the AEX-RT group will undergo 3 months of aerobic exercise training to increase skeletal muscle capillarization followed by 3 months of resistance training Participants in the RT-AEX group will undergo 3 months of resistance training followed by 3 months of aerobic exercise training Before and after the interventions participants will undergo assessments of muscle size strength and capillarization as well as assessments of physical function
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None