Ignite Creation Date:
2024-05-06 @ 1:14 PM
Last Modification Date:
2024-10-26 @ 1:11 PM
Study NCT ID:
NCT03973528
Status:
COMPLETED
Last Update Posted:
2022-03-22
First Post:
2019-06-02
Brief Title:
Primary Efficacy Evaluation of Traditional Chinese Medicine in Treating Older Infertile Women
Sponsor:
Chang Gung Memorial Hospital
Organization:
Chang Gung Memorial Hospital
Study Overview
Official Title:
A Preliminary Evaluation of the Efficacy of Traditional Chinese Medicine in Treating Elderly Women With Infertility
Status:
COMPLETED
Status Verified Date:
2022-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is a preliminary evaluation of the efficacy of traditional Chinese medicine in the treatment of elderly infertile women
Detailed Description:
Research design initial acceptance of 60 people 30 in the no intervention group and 30 in the experimental group
The no intervention group no use Traditional Chinese medicine The experimental group use Traditional Chinese medicine Affect natural pregnancy and IVF success factors the quality of ovarian function plays a very important role Currently used to predict ovarian follicle inventory indicators including age the total number of small sized ovarian follicles the first three days of menstrual follicle-stimulating hormone Anti-Mullerian hormone inhibin-B
Research Analysis Chang Gung Memorial Hospital infertility patients using traditional Chinese medicine more than 40-year-old infertility patients the most commonly used compound is Zuo Gui Wan Chinese medicine believes that elderly women with infertility ovulation poor the main pathogenesis of kidney deficiency The proportion of domestic infertility patients has increased year by year Traditional Chinese medicine had become popular and acceptable but the substantial evidence and treatment consensus of infertility are scanty
Due to the outbreak of the new crown pneumonia epidemic which made it difficult to accept the case Only 17 subjects in the experimental group completed the test The average age of the subjects was 4011 309 years old and 9 of them were over 40 years old The AMH before the test was all below 12 After three months of treatment with traditional Chinese medicine 16 subjects had an increase in the number of small sized ovarian follicles The average total number of small ovarian follicles before the test was 306090 and the average increased to 453146 after treatment P005 which was statistically significant Eleven subjects showed a decrease in follicle-stimulating hormone on the third day of menstruation after treatment 9 subjects showed an increase in anti-Mullerian hormone AMH value after treatment and 3 subjects had anti-Mullerian hormone AMH values higher than 12 after treatment but they did not reach statistical significance
The no intervention group no use Traditional Chinese medicine The experimental group use Traditional Chinese medicine Affect natural pregnancy and IVF success factors the quality of ovarian function plays a very important role Currently used to predict ovarian follicle inventory indicators including age the total number of small sized ovarian follicles the first three days of menstrual follicle-stimulating hormone Anti-Mullerian hormone inhibin-B
Research Analysis Chang Gung Memorial Hospital infertility patients using traditional Chinese medicine more than 40-year-old infertility patients the most commonly used compound is Zuo Gui Wan Chinese medicine believes that elderly women with infertility ovulation poor the main pathogenesis of kidney deficiency The proportion of domestic infertility patients has increased year by year Traditional Chinese medicine had become popular and acceptable but the substantial evidence and treatment consensus of infertility are scanty
Due to the outbreak of the new crown pneumonia epidemic which made it difficult to accept the case Only 17 subjects in the experimental group completed the test The average age of the subjects was 4011 309 years old and 9 of them were over 40 years old The AMH before the test was all below 12 After three months of treatment with traditional Chinese medicine 16 subjects had an increase in the number of small sized ovarian follicles The average total number of small ovarian follicles before the test was 306090 and the average increased to 453146 after treatment P005 which was statistically significant Eleven subjects showed a decrease in follicle-stimulating hormone on the third day of menstruation after treatment 9 subjects showed an increase in anti-Mullerian hormone AMH value after treatment and 3 subjects had anti-Mullerian hormone AMH values higher than 12 after treatment but they did not reach statistical significance
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| Chang Gung MH | OTHER_GRANT | CMRPG3H1931 | None |