Ignite Creation Date:
2024-05-05 @ 4:56 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00343993
Status:
UNKNOWN
Last Update Posted:
2007-04-04
First Post:
2006-06-23
Brief Title:
Noninvasive Positive Pressure Ventilation for ALIARDSa Multicentre Randomized Controlled Trial
Sponsor:
Beijing Chao Yang Hospital
Organization:
Beijing Chao Yang Hospital
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2007-04
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
with appropriate inspired oxygen concentrations NPPV would prevent intubation and hence avert the poor outcome associated with the need of invasive ventilation in patients with ALIARDS
Detailed Description:
Noninvasive positive-pressure ventilation NPPV is increasingly being used in the care of patients suffering acute respiratory failure High-level evidence supports the use of NPPV to treat exacerbation of chronic obstructive pulmonary disease COPD More recently NIV has shown to reduce the need for intubation in selected groups of patients with severe cardiogenic pulmonary edema immunosuppression and respiratory failure after lung resection In their subgroup analysis of the five randomized control trials however patients with acute lung injury ALI or ARDS still couldnt avoid intubation and death even treated with NPPV Till now there has been no randomized controlled study of NPPV in patients with ALI or ARDS We hypothesized that in patients with ALIARDS early use of NPPV providing appropriate inspired oxygen concentrations would prevent intubation as the primary end-point variable hence avert the poor outcome associated with the need of invasive ventilation Accordingly we conducted a prospective randomized controlled trial to assess the efficacy of NPPV compared with a standard regime consisting of high-concentration oxygen therapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None