Ignite Creation Date:
2024-05-06 @ 1:10 PM
Last Modification Date:
2024-10-26 @ 1:10 PM
Study NCT ID:
NCT03950141
Status:
UNKNOWN
Last Update Posted:
2019-05-15
First Post:
2018-11-18
Brief Title:
Apatinib Combined With S-1 as Maintenance Therapy for HER-2 Negatived Gastric Cancer
Sponsor:
Beijing Hospital
Organization:
Beijing Hospital
Study Overview
Official Title:
Apatinib Combined With S-1 as Maintenance Therapy for HER-2 Negatived Gastric Cancer Treated With 4 Cycles Chemotherapy Valued as Stable Disease SD
Status:
UNKNOWN
Status Verified Date:
2019-05
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Apatinib is a novel drug which was produced by Jiangsu Hengrui Medicine CoLtd in China It is approved in advanced gastric cancerGC The investigators just want to design such kind of trail to prove its effect when combined with S-1 as maintenance in advanced HER-2 negatived GC treated with 4 cycles chemotherapy and valued as SD Investigators will evaluate progression free survival PFS and overall survival OS
Detailed Description:
GC is the second most common cause of cancer-related deaths worldwide Most patients are diagnosed with unresectable advanced or metastatic stage disease losing the radical surgery opportunity Till now there is no novel targeted drug which can increase the OS for advanced GC patients except HER-2 positive patients
Approximate 30 patients with unresectable GC treated with 4 cycles chemotherapy and valued as stable disease will be enrolled in this studyThe investigators will evaluate the efficacy and security of apatinib and S-1 as maintenance therapy
Approximate 30 patients with unresectable GC treated with 4 cycles chemotherapy and valued as stable disease will be enrolled in this studyThe investigators will evaluate the efficacy and security of apatinib and S-1 as maintenance therapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None