Ignite Creation Date:
2024-05-05 @ 4:55 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00345436
Status:
COMPLETED
Last Update Posted:
2017-07-02
First Post:
2006-06-27
Brief Title:
Exercise in Insulin-Resistant Minority Adolescents
Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
An Exercise Intervention in Insulin-Resistant Minority Adolescents
Status:
COMPLETED
Status Verified Date:
2011-05-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Insulin resistance often accompanied by obesity plays a major role in the development of type 2 diabetes This phenomenon may be related with the fact that American adolescents are now becoming less physically active in early puberty explaining the largely pubertal and post-pubertal onset of type 2 diabetes in adolescence Although regular physical activity has been suggested to attenuate obesity and prevent type 2 diabetes in high-risk children and adolescents the magnitude of exercise training-induced improvement in the risk factors for type 2 diabetes has been only recently studied in adults and studied very little in pediatric populations It is clear that exercise diet and genetics all contribute to the development of type 2 diabetes in children However the few studies that have been done to dissect the relative contributions of these three risk factors have generally used only lipid profiles as the end point There have been a number of recent advances in our understanding of the molecular basis of type 2 diabetes particularly with regards to insulin regulatory pathways modulated by exercise within muscle tissue
Detailed Description:
Insulin resistance often accompanied by obesity plays a major role in the development of type 2 diabetes This phenomenon may be related with the fact that American adolescents are now becoming less physically active in early puberty explaining the largely pubertal and post-pubertal onset of type 2 diabetes in adolescence Although regular physical activity has been suggested to attenuate obesity and prevent type 2 diabetes in high-risk children and adolescents the magnitude of exercise training-induced improvement in the risk factors for type 2 diabetes has been only recently studied in adults and studied very little in pediatric populations It is clear that exercise diet and genetics all contribute to the development of type 2 diabetes in children However the few studies that have been done to dissect the relative contributions of these three risk factors have generally used only lipid profiles as the end point There have been a number of recent advances in our understanding of the molecular basis of type 2 diabetes particularly with regards to insulin regulatory pathways modulated by exercise within muscle tissue
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 06-CH-N094 | None | None | None |