Ignite Creation Date:
2024-05-05 @ 4:55 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00342810
Status:
COMPLETED
Last Update Posted:
2019-12-17
First Post:
2006-06-19
Brief Title:
Analyses of Existing Framingham Data
Sponsor:
National Eye Institute NEI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Continued Analyses of Epidemiologic Risk Factors Using Existing Framingham Eye and Heart Study Data
Status:
COMPLETED
Status Verified Date:
2018-04-25
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Since 1948 the Framingham Study has examined a group of men and women every two years for the primary purpose of studying the incidence and prevalence of cardiovascular disease and its risk factors In 1971 the Framingham Study began a study of the offspring of the original group including data collection on blood pressure cigarette smoking weight and other factors that are of interest to studies of eye disease Researchers gave eye exams to some of the original group and to the offspring group Data from these eye exams have been used to examine risk factors for cataracts diabetic retinopathy myopia and glaucoma
The purpose of this study is to use the previously collected data for continued research on eye-related disorders No new eye examinations will be conducted
The purpose of this study is to use the previously collected data for continued research on eye-related disorders No new eye examinations will be conducted
Detailed Description:
We propose to continue to analyze existing Framingham Eye and Heart Study data to identify possible risk factors for various eye diseases Originally begun in 1948 by the National Heart Lung and Blood Institute NHLBI the Framingham Heart Study has been examining a population-based cohort of men and women biennially since 1948 for the primary purpose of studying the incidence and prevalence of cardiovascular disease and its risk factors In 1971 the Heart Study began a prospective study of the offspring of the original cohort The Heart Study has collected data on blood pressure cigarette smoking weight and many other factors of interest for epidemiologic studies of eye disease Eye examinations were conducted on the survivors of the original cohort in a collaborative effort between the NEI and the NHLBI between 1973 and 1975 Framingham Eye Study I FES I and then again between 1986 and 1989 Framingham Eye Study II FES II Eye examinations were conducted on the Offspring Cohort from 1989 to 1991 Framingham Offspring Eye Study FOES The Framingham data are unique in allowing epidemiologic studies with both cross sectional and longitudinal designs Over the years data from the Heart Study and the various eye studies have been used to examine demographic and risk factor characteristics for cataract diabetic retinopathy myopia and glaucoma To date this collaborative effort has yielded 31 publications by the National Eye Institutes Division of Epidemiology and Clinical Research Rita Hiller is an author of 11 This proposal is for the continued use of the previously collected Framingham data All studies will be done in collaboration with Heart Study investigators from Boston University which manages the study and conducts annual IRB reviews No new eye examinations will be done
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 03-EI-N232 | None | None | None |