Ignite Creation Date:
2025-12-24 @ 4:59 PM
Ignite Modification Date:
2025-12-26 @ 7:51 PM
Study NCT ID:
NCT04609150
Status:
UNKNOWN
Last Update Posted:
2020-11-06
First Post:
2020-10-07
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Vertebral Fat Quantitative MRI as a Marker of Bone Fragility in Multiple Myeloma (MYELOMEFRAGIQUANTI)
Sponsor:
Assistance Publique - Hôpitaux de Paris
Organization:
Study Overview
Official Title:
Assessment of Vertebral Fat Quantitative MRI as a Marker of Bone Fragility in Patients With Multiple Myeloma
Status:
UNKNOWN
Status Verified Date:
2020-09
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Multiple myeloma is a disease that causes increased bone fragility which is often revealed or complicated by vertebral fractures. Invasion of bone marrow by tumor plasma cells leads to bone destruction and reduced fat fraction. The main objective is to assess the correlation between vertebral bone marrow fat fraction and bone fragility represented by a severity score of vertebral fractures. The secondary objective is to assess the correlation with clinical and biological prognostic factors and scores..
Detailed Description:
Patients treated with vertebroplasty will be included during the period of the study, retrospectively or prospectively.
Mains collected data are represented by :
* Bone marrow fat fraction determined by MRI
* Severity score for vertebral fractures
* Clinical prognostic factors
* Biological prognostic factors
* Clinico-biological scores Descriptive statistics and correlation analyses will be performed between the measured parameters.
Mains collected data are represented by :
* Bone marrow fat fraction determined by MRI
* Severity score for vertebral fractures
* Clinical prognostic factors
* Biological prognostic factors
* Clinico-biological scores Descriptive statistics and correlation analyses will be performed between the measured parameters.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: