Ignite Creation Date:
2024-05-06 @ 1:02 PM
Last Modification Date:
2024-10-26 @ 1:07 PM
Study NCT ID:
NCT03911609
Status:
UNKNOWN
Last Update Posted:
2019-04-11
First Post:
2019-04-03
Brief Title:
Cardiovascular Autonomic Function and Endogenous Pain Modulation
Sponsor:
Marquette University
Organization:
Marquette University
Study Overview
Official Title:
The Influence of Cardiovascular Autonomic Function on Endogenous Pain Modulation Before and After Exercise and Cognitive Task in Fibromyalgia
Status:
UNKNOWN
Status Verified Date:
2019-04
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The study has three aims
1 To investigate the influence of cardiovascular autonomic function on pain sensitivity at rest in patients with fibromyalgia and age- and sex-matched controls
2 To investigate the influence of cardiovascular autonomic function at baseline and during exercise on the pain response following submaximal isometric exercise
3 To study the relation between the pain response following physical and cognitive tasks exercise and mental math respectively
1 To investigate the influence of cardiovascular autonomic function on pain sensitivity at rest in patients with fibromyalgia and age- and sex-matched controls
2 To investigate the influence of cardiovascular autonomic function at baseline and during exercise on the pain response following submaximal isometric exercise
3 To study the relation between the pain response following physical and cognitive tasks exercise and mental math respectively
Detailed Description:
Fibromyalgia FM affects 2 -8 of the population with a higher prevalence in women than men People with FM report widespread pain that impacts their quality of life Patients may also experience other symptoms besides pain such as depression anxiety fatigue sleep difficulties and others Exercise is one of the interventions that have been shown to reduce pain in chronic pain populations The phenomenon by which exercise reduces pain sensitivity is known as exercise-induced hypoalgesia EIH Although exercise is strongly recommended by American Pain Society guideline for the treatment of FM some patients with FM report an increase in pain and worsening symptoms following acute exercise The worsening of symptoms may impact adherence to exercise training Why some people with FM report pain exacerbation while others report pain relief following exercise is not known
This study aims at assessing the influence of the cardiovascular autonomic nervous system on pain sensitivity at rest and following exercise in patients with fibromyalgia and pain-free individuals
This study aims at assessing the influence of the cardiovascular autonomic nervous system on pain sensitivity at rest and following exercise in patients with fibromyalgia and pain-free individuals
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None