Ignite Creation Date:
2024-05-06 @ 1:00 PM
Last Modification Date:
2024-10-26 @ 1:07 PM
Study NCT ID:
NCT03907293
Status:
COMPLETED
Last Update Posted:
2021-01-13
First Post:
2019-03-19
Brief Title:
Effect of a Cardiac Rehabilitation CR Programme on Molecular Mechanisms
Sponsor:
University of Ulster
Organization:
University of Ulster
Study Overview
Official Title:
Effect of a Cardiac Rehabilitation CR Programme on Protein Molecules Associated With Arterial Function and an Exploration of Reasons for Agreeing or Declining to Participate in a CR Programme
Status:
COMPLETED
Status Verified Date:
2021-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will evaluate the effect of a cardiac rehabilitation CR programme on blood protein molecules that may improve the function of arteries in coronary artery disease CAD patients who have suffered a heart attack CAD patients who have either agreed or disagreed to take part in a CR programme will be recruited This will allow a comparison of the study measurements between a group of patients who complete a CR programme and a group of patients who do not
The other objective of this study is to perform interviews with the study participants and their significant others ie spouse family member or a close friend to listen to the reasons why patients agreed or disagreed to take part in a CR programme
The other objective of this study is to perform interviews with the study participants and their significant others ie spouse family member or a close friend to listen to the reasons why patients agreed or disagreed to take part in a CR programme
Detailed Description:
An exercise-based cardiac rehabilitation CR programme is an established method of secondary prevention of coronary artery disease CAD Moreover there is a body of evidence that supports the ability of this intervention to reduce hospital readmissions and cardiovascular mortality However despite the proven benefit CR programmes are underutilised worldwide Moreover the molecular mechanisms responsible for orchestrating the beneficial physiological adaptations induced by a CR programme are poorly understood
Therefore this study will evaluate the effect of a CR programme on novel molecular mechanisms and endothelial function in post-myocardial infarction CAD patients Additionally semi-structured interviews will be conducted with study participants and their significant others ie spouse family member or a close friend to explore the reasons why patients may agree or disagree to take part in a CR programme Altogether this study will provide physiological and detailed qualitative information that may help to provoke an increased participation in CR programmes
Therefore this study will evaluate the effect of a CR programme on novel molecular mechanisms and endothelial function in post-myocardial infarction CAD patients Additionally semi-structured interviews will be conducted with study participants and their significant others ie spouse family member or a close friend to explore the reasons why patients may agree or disagree to take part in a CR programme Altogether this study will provide physiological and detailed qualitative information that may help to provoke an increased participation in CR programmes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None