Viewing Study NCT00342485



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Last Modification Date: 2024-10-26 @ 9:25 AM
Study NCT ID: NCT00342485
Status: COMPLETED
Last Update Posted: 2017-07-02
First Post: 2006-06-19

Brief Title: In Vitro Study of Peripheral Blood Mononuclear Cell Function in Healthy Individuals and Patients
Sponsor: National Cancer Institute NCI
Organization: National Institutes of Health Clinical Center CC

Study Overview

Official Title: In Vitro Study of Peripheral Blood Mononuclear Cell Function in Healthy Individuals and Patients
Status: COMPLETED
Status Verified Date: 2008-03-03
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Peripheral blood mononuclear cells PBMC will be collected from healthy volunteers and patients who present with different diseases that involve or implicate the immune system dysregulation HIV infection autoimmune diseases and cancer These PBMC will be studied in vitro for a number of functional parameters including generating soluable factors that inhibit HIV infection developing patterns of immune dysregulation and inducing apoptotic T cell death The purpose of such studies is to obtain insight into the mechanisms of natural resistance to viral infections AIDS pathogenesis and disease-induced immune dysregulation
Detailed Description: Peripheral blood mononuclear cells PBMC will be collected from healthy volunteers and patients who present with different diseases that involve or implicate the immune system dysregulation HIV infection autoimmune diseases and cancer These PBMC will be studied in vitro for a number of functional parameters including generating soluable factors that inhibit HIV infection developing patterns of immune dysregulation and inducing apoptotic T cell death The purpose of such studies is to obtain insight into the mechanisms of natural resistance to viral infections AIDS pathogenesis and disease-induced immune dysregulation

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None
Secondary IDs
Secondary ID Type Domain Link
OH93-NC-N010 None None None