Ignite Creation Date:
2024-05-05 @ 4:54 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00344253
Status:
COMPLETED
Last Update Posted:
2012-12-03
First Post:
2006-06-22
Brief Title:
Randomized Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediate Uveitis
Sponsor:
Heidelberg University
Organization:
Heidelberg University
Study Overview
Official Title:
A Monocentric Randomized Controlled Trial to Test the Efficacy of Interferon-beta in the Treatment of Disseminated Encephalomyelitis ED-Associated and Primary Intermediate Uveitis in Comparison to Standard Treatment TEAM
Status:
COMPLETED
Status Verified Date:
2012-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to investigate if interferon beta is superior to the standard treatment with Methotrexate for the treatment of intermediate uveitis and macular edema
Detailed Description:
Deuter et al were the first to show the anti-edematous effect of interferon alpha on inflammatory macular edema Deuter C M E Kötter I Günaydin I Zierhut M Treatment of the Cystoid Macular Oedema in Behçets Disease with Interferon Alfa-2a Retina in press In an interventional multi-centric pilot-study we could demonstrate a positive effect of interferon beta on ED associated uveitis especially in reducing the macular edema Undesired effects of the treatment were not observed
Thus we want to test the efficacy and safety of interferon beta compared to standard treatment with methotrexate in a prospective clinically controlled trial on patients who suffer from intermediate uveitis with inflammatory macular edema who either have associated ED or have no systemic disease association ie primary uveitis
Thus we want to test the efficacy and safety of interferon beta compared to standard treatment with methotrexate in a prospective clinically controlled trial on patients who suffer from intermediate uveitis with inflammatory macular edema who either have associated ED or have no systemic disease association ie primary uveitis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None