Ignite Creation Date:
2024-05-05 @ 4:54 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00341952
Status:
COMPLETED
Last Update Posted:
2020-11-27
First Post:
2006-06-19
Brief Title:
Interdisciplinary Case-Control Study of Non-Hodgkins Lymphoma
Sponsor:
National Cancer Institute NCI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Interdisciplinary Case-Control Study of Non-Hodgkins Lymphoma
Status:
COMPLETED
Status Verified Date:
2020-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Non-Hodgkins lymphoma NHL incidence rates have risen three percent per year in the US for four decades Mortality from NHL has risen 16 percent compared with 02 percent for all cancers combined This epidemic curve appears in both sexes and around the world suggesting the possibility of an etiologic agent increasing in prevalence in the general environment Recent research has identified several possible candidates including pesticides other organochlorines drinking water nitrates and sunlight There is an urgent need to evaluate whether these common exposures are contributing to the rapid rise in NHL and to investigate other hypothesized risk factors such as viruses medical conditions hair dye use and genetic factors The purpose of this study is to examine the contribution to NHL risk of these important environmental occupational viral medical and personal exposures and to pursue important leads emerging from on-going NHL research This multidisciplinary population-based case-control study will involve personal interviews to collect information on demographics residential history pesticide use and occupational exposures self-administered questionnaires to collect information on diet family and medical history and other exposures tap water and carpet dust sampling to collect information on nitrate and pesticide exposures and blood sampling for measurements of compounds in the serum antibodies to viruses and examination of genetic polymorphisms
Detailed Description:
Non-Hodgkins lymphoma NHL incidence rates have risen three percent per year in the US for four decades Mortality from NHL has risen 16 percent compared with 02 percent for all cancers combined This epidemic curve appears in both sexes and around the world suggesting the possibility of an etiologic agent increasing in prevalence in the general environment Recent research has identified several possible candidates including pesticides other organochlorines drinking water nitrates and sunlight There is an urgent need to evaluate whether these common exposures are contributing to the rapid rise in NHL and to investigate other hypothesized risk factors such as viruses medical conditions hair dye use and genetic factors The purpose of this study is to examine the contribution to NHL risk of these important environmental occupational viral medical and personal exposures and to pursue important leads emerging from on-going NHL research This multidisciplinary population-based case-control study will involve personal interviews to collect information on demographics residential history pesticide use and occupational exposures self-administered questionnaires to collect information on diet family and medical history and other exposures tap water and carpet dust sampling to collect information on nitrate and pesticide exposures and blood sampling for measurements of compounds in the serum antibodies to viruses and examination of genetic polymorphisms
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| OH98-C-N022 | None | None | None |