Ignite Creation Date:
2024-05-05 @ 4:54 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00342329
Status:
COMPLETED
Last Update Posted:
2017-07-02
First Post:
2006-06-19
Brief Title:
Lupus Nephritis Role of Environmental and Occupational Exposures
Sponsor:
National Institute of Environmental Health Sciences NIEHS
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Lupus Nephritis Role of Environmental and Occupational Exposures
Status:
COMPLETED
Status Verified Date:
2007-03-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to examine hormonal and environmental risk factors and possible gene-environmental interactions involved in the etiology of lupus nephritis Our study will focus on exposures to occupational and environmental agents that have been linked to the development of systemic lupus erythematosus SLE or renal disease eg silica dust smoking We will also assess potential gene environment interactions We will examine these exposures in 100 patients with renal biopsy with documented proliferative or membraneous nephritis We will compare exposures in the lupus nephritis patients to lupus patients who do not have nephritis and to normal controls who have participated in the Carolina Lupus Study One hundred lupus nephritis patients age 18 years or older of both genders and all races will be identified through the Glomerular Disease Collaborative Network GDCN Nephropathology database and participating nephrologists at the Medical University of South Carolina Duke University Medical Center and the East Carolina Medical School
Detailed Description:
The purpose of this study is to examine hormonal and environmental risk factors and possible gene-environmental interactions involved in the etiology of lupus nephritis Our study will focus on exposures to occupational and environmental agents that have been linked to the development of systemic lupus erythematosus SLE or renal disease eg silica dust smoking We will also assess potential gene environment interactions We will examine these exposures in 100 patients with renal biopsy with documented proliferative or membraneous nephritis We will compare exposures in the lupus nephritis patients to lupus patients who do not have nephritis and to normal controls who have participated in the Carolina Lupus Study One hundred lupus nephritis patients age 18 years or older of both genders and all races will be identified through the Glomerular Disease Collaborative Network GDCN Nephropathology database and participating nephrologists at the Medical University of South Carolina Duke University Medical Center and the East Carolina Medical School
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 01-E-N154 | None | None | None |