Viewing Study NCT00340626



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Study NCT ID: NCT00340626
Status: COMPLETED
Last Update Posted: 2020-03-13
First Post: 2006-06-19

Brief Title: Genetic Analysis of Hereditary Non-Syndromic Oral Clefts
Sponsor: National Human Genome Research Institute NHGRI
Organization: National Institutes of Health Clinical Center CC

Study Overview

Official Title: Genetic Analysis of Hereditary Non-Syndromic Oral Clefts
Status: COMPLETED
Status Verified Date: 2020-03
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: In a collaborative effort with the IBN AL-NAFEES Hospital Damascus Syrian Arab Republic individuals from multiplex families determined to have hereditary oral clefts will be studied The purpose of this study is to identify the genes involved in heritable oral clefts by linkage analysis and gene mapping strategies Characterization of genes involved in inherited oral clefts could provide important insight into the inheritance and pathogenesis of this disease
Detailed Description: In a collaborative effort with the IBN AL-NAFEES Hospital Damascus Syrian Arab Republic individuals from multiplex families determined to have hereditary oral clefts will be studied Healthy Syrian individuals with no family history of oral clefts will also be enrolled as a comparison group The purpose of this study is to identify the genes involved in heritable oral clefts by linkage analysis and gene mapping strategies Characterization of genes involved in inherited oral clefts could provide important insight into the inheritance and pathogenesis of this disease All families are enrolled into the study by our Syrian collaborators under Ethics Board approval from the IBN AL-NAFEES Hospital and only coded phenotype data and coded biospecimens are ever received at the NIH

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None
Secondary IDs
Secondary ID Type Domain Link
OH97-HG-N035 None None None