Ignite Creation Date:
2024-05-05 @ 4:54 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00344669
Status:
COMPLETED
Last Update Posted:
2006-10-17
First Post:
2006-06-14
Brief Title:
Effect of Mass Deworming on Child Growth
Sponsor:
Makerere University
Organization:
Makerere University
Study Overview
Official Title:
Increased Weight Gain in Preschool Children Due to Mass Albendazole Treatment Given During Child Health Days in Uganda
Status:
COMPLETED
Status Verified Date:
2006-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of the study was to determine whether periodical mass deworming improves growth in children below six years of age
Detailed Description:
Many children in developing countries get slowed growth because of heavy loads of intestinal helminths Quite often treatment is not sought because there may not be any obvious symptoms Slowed growth may manifest as low weight for age or low height for age
The objective of the study was to estimate the effectiveness of the delivery of an anthelmintic drug through a community child health program on the weight gain of preschool aged children
Design This was a cluster randomized controlled trial in 48 parishes in Eastern Uganda All 48 parishes were participating in a new program for child health 24 were randomly assigned to offer to children an additional service of anthelmintic treatment The intervention was 400 mg of albendazole added to the standard services at child days over a 3 years period All children were offered the drug and the main outcome measure was weight gain
Results A total of 27995 children were recruited into the 2 arms of the study with 14940 in the treatment arm and 13055 in the control arm The intervention arm got an increase in weight gain of about 10 166 grams per child per year CI 16-316 above expected weight gain when treatment was taken twice a year and an increase of 5 when treatment was received approximately annually
Conclusion The inclusion of deworming in regularly scheduled health services appears practical and capable of increasing child growth
The objective of the study was to estimate the effectiveness of the delivery of an anthelmintic drug through a community child health program on the weight gain of preschool aged children
Design This was a cluster randomized controlled trial in 48 parishes in Eastern Uganda All 48 parishes were participating in a new program for child health 24 were randomly assigned to offer to children an additional service of anthelmintic treatment The intervention was 400 mg of albendazole added to the standard services at child days over a 3 years period All children were offered the drug and the main outcome measure was weight gain
Results A total of 27995 children were recruited into the 2 arms of the study with 14940 in the treatment arm and 13055 in the control arm The intervention arm got an increase in weight gain of about 10 166 grams per child per year CI 16-316 above expected weight gain when treatment was taken twice a year and an increase of 5 when treatment was received approximately annually
Conclusion The inclusion of deworming in regularly scheduled health services appears practical and capable of increasing child growth
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None