Ignite Creation Date:
2024-05-05 @ 11:08 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001233
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Study of Children at Risk for Disruptive Behavior Disorders
Sponsor:
National Institute of Mental Health NIMH
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
A Longitudinal Study of Children at Risk for Disruptive Behavior Disorders Transitions From Early Childhood to Middle Childhood and Adolescence
Status:
COMPLETED
Status Verified Date:
2000-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
A conduct disorder is characterized by repetitive and persistent patterns of behavior where the basic rights of others and rules are violated
This study investigates characteristics of children and their surroundings environments that place them at risk for the development of disruptive behavior disorders and associated disorders of anxiety and mood Children ages 4 - 5 with moderate subclinical and severe clinical rates of misconduct during the preschool period are compared to low risk children Children and their families were recruited from 1989-1991 and are being studied at five specific times
1 Preschool 4 - 5 years
2 Early childhood 6 - 7 years
3 Middle childhood 9 - 10 years
4 Early adolescence 13 - 14 years
5 Mid-adolescence 15 - 16 years
Researchers will look closely at biological intellectual emotional and behavioral factors that are thought to protect against andor increase the risk of developing a conduct problem These factors have been studied in older children and are shown to be associated with disruptive behavior disorders
The goals of this research study are
1 Create a database showing the characteristics of the development of disruptive behavior problems
2 Identify the key risk and protective factors that contribute to the stability or change in behavior problems over time
3 Identify the ways that children interact socially and relate them to the possibility of developing a problem of behavior
4 Identify how experiences and the emotions associated with experiences may play a role in the development of related psychiatric conditions like depression and anxiety
5 Establish measures of the different components of negative emotions associated with disruptiveantisocial anxiety and mood disorders
This study investigates characteristics of children and their surroundings environments that place them at risk for the development of disruptive behavior disorders and associated disorders of anxiety and mood Children ages 4 - 5 with moderate subclinical and severe clinical rates of misconduct during the preschool period are compared to low risk children Children and their families were recruited from 1989-1991 and are being studied at five specific times
1 Preschool 4 - 5 years
2 Early childhood 6 - 7 years
3 Middle childhood 9 - 10 years
4 Early adolescence 13 - 14 years
5 Mid-adolescence 15 - 16 years
Researchers will look closely at biological intellectual emotional and behavioral factors that are thought to protect against andor increase the risk of developing a conduct problem These factors have been studied in older children and are shown to be associated with disruptive behavior disorders
The goals of this research study are
1 Create a database showing the characteristics of the development of disruptive behavior problems
2 Identify the key risk and protective factors that contribute to the stability or change in behavior problems over time
3 Identify the ways that children interact socially and relate them to the possibility of developing a problem of behavior
4 Identify how experiences and the emotions associated with experiences may play a role in the development of related psychiatric conditions like depression and anxiety
5 Establish measures of the different components of negative emotions associated with disruptiveantisocial anxiety and mood disorders
Detailed Description:
This study investigates characteristics of children and their environments that place them at risk for the development of disruptive behavior disorders and co-morbid internalizing problems anxiety and mood disorders Children ages 4-5 with moderate subclinical and high clinical rates of misconduct during the preschool period are compared with low risk children Children and their families are studied again at four later time points a early childhood 6-7 yrs b middle childhood 9-10 yrs c early adolescence 13-14 yrs and d mid-adolescence 15-16 yrs Assessments of children include dimensions of biological cognitive affective emotional and behavioral functioning that have been identified in research with older children as putative risk and protective factors in the development of conduct problems Socialization experiences within and outside the family also hypothesized to influence developmental trajectories are examined Currently Time 4 assessments are being conducted with three-quarters of the research subjects tested Behavior problems show significant stability across the first three time periods However some children improve over time changes that result in part from more optimal environmental conditions Different patterns of emotion dysregulation ANS and HPA activity in antisocial preschool children predict different types of externalizing problems at later time points Behavior problems and their correlates differ for young disruptive boys and girls Oppositional aggressive girls are more likely to have co-morbid internalizing problems and emotion regulation patterns that may decrease risk for continued antisocial behavior but increase risk for depression and anxiety later in development
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 88-M-0217 | None | None | None |