Ignite Creation Date:
2024-05-05 @ 4:53 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00339170
Status:
COMPLETED
Last Update Posted:
2020-03-30
First Post:
2006-06-16
Brief Title:
Cognitive Training and Enhanced Supported Employment in Schizophrenia
Sponsor:
Yale University
Organization:
Yale University
Study Overview
Official Title:
Cognitive Training and Enhanced Supported Employment
Status:
COMPLETED
Status Verified Date:
2016-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will evaluate the effectiveness of a computer-based cognitive enhancement program plus a work therapy program at improving productivity work performance and quality of life in schizophrenic individuals
Detailed Description:
Schizophrenia is a chronic severe and disabling brain disorder that affects 24 million people in the United States Individuals with schizophrenia may have difficulties with cognitive functioning including problems with attention memory and organizational thought processes These factors can lead to decreased productivity and poor work performance which may make holding a job difficult Research has shown that certain types of psychological therapies such as cognitive behavioral therapy are useful in reducing the severity of schizophrenic symptoms The purpose of this study is to determine whether a computer-based cognitive enhancement training program in combination with a work therapy program will enhance workplace performance productivity and quality of life in individuals with schizophrenia
This study will enroll individuals with schizophrenia or schizoaffective disorder Participants will undergo a cognitive assessment at baseline They will then be randomly assigned to either a 12-month cognitive enhancement training program plus a 12-month work therapy program or a 12-month work therapy program alone Participants in the cognitive enhancement training program will receive feedback on their cognitive strengths and weaknesses based on the outcomes of the baseline assessment The training component will be comprised of 150 computer-based exercises that focus on improving memory attention and organizational skills Participants will attend two weekly meetings one will focus on providing feedback regarding goal-setting and problem-solving and the other will focus on improving verbal skills and social information processing Individuals taking part only in the work therapy program will attend two non-cognitive discussion groups per week All participants will work up to 20 hours a week in an approved work environment and will have access to appropriate support services Following the end of the program participants will have the option of working an additional 12 months Schizophrenia symptoms quality of life and neuropsychological and rehabilitation effects will be assessed at the end of Years 1 and 2
This study will enroll individuals with schizophrenia or schizoaffective disorder Participants will undergo a cognitive assessment at baseline They will then be randomly assigned to either a 12-month cognitive enhancement training program plus a 12-month work therapy program or a 12-month work therapy program alone Participants in the cognitive enhancement training program will receive feedback on their cognitive strengths and weaknesses based on the outcomes of the baseline assessment The training component will be comprised of 150 computer-based exercises that focus on improving memory attention and organizational skills Participants will attend two weekly meetings one will focus on providing feedback regarding goal-setting and problem-solving and the other will focus on improving verbal skills and social information processing Individuals taking part only in the work therapy program will attend two non-cognitive discussion groups per week All participants will work up to 20 hours a week in an approved work environment and will have access to appropriate support services Following the end of the program participants will have the option of working an additional 12 months Schizophrenia symptoms quality of life and neuropsychological and rehabilitation effects will be assessed at the end of Years 1 and 2
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01MH061493 | NIH | None | None |
| DSIR AT-RH | US NIH GrantContract | None | httpsreporternihgovquickSearchR01MH061493 |