Ignite Creation Date:
2024-05-05 @ 4:53 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00336050
Status:
UNKNOWN
Last Update Posted:
2016-07-29
First Post:
2006-06-09
Brief Title:
Effect of Air Pollution on Long-Term Asthma Severity and Lung Function in Children
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
Fresno Asthmatic Childrens Environment Study
Status:
UNKNOWN
Status Verified Date:
2009-02
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
FACES
Brief Summary:
Asthma can be caused by many factors including mold pollen and other airborne pollutants The purpose of this study is to evaluate the effect that air pollution has on the long-term severity of asthma symptoms and lung function in children
Detailed Description:
Asthma prevalence has steadily increased in the United States since the early 1980s currently more than 20 million people are diagnosed with asthma including 9 million children Asthma can be caused by many factors including pollen dust tobacco smoke and other allergens Research has shown that even short-term increases in daily levels of air pollution can trigger an increase in asthma symptoms in some individuals More research is needed to determine how short-term increases in air pollution affect the severity of asthma later in life The Environmental Protection Agency EPA has constructed research monitoring stations known as Supersites to advance the understanding of the effect of airborne pollutants on the health of individuals Data collected from the Supersites provide important information regarding air pollution and air quality levels This study will use air pollution measurements obtained from the Fresno California Supersite to monitor participants exposure to air pollution The purpose of the study is to determine if children who experience a worsening of asthma symptoms due to an increase in air pollution have greater long-term asthma severity and decreased lung function compared to children who do not experience a worsening of symptoms when exposed to air pollution
This study will enroll children with asthma who live within 20 kilometers of the EPA Supersite in Fresno California Participants will have study visits twice a year for up to 2 ½ years At study entry participants will undergo a skin prick allergy test and complete a dietary questionnaire At each study visit a respiratory illness questionnaire will be completed and participants will undergo spirometry tests to measure lung function In addition to the twice yearly visits participants will take part in three 14-day sessions each year during which daily diaries will be completed and spirometry will be performed twice a day Study staff will gather detailed air pollution information from the Supersite mobile monitoring trailers and inside and outside the participants homes
Beginning in May 2006 participants will take part in only one study visit and two 14-day sessions each year Air pollution measurements will be obtained from only the Supersite To estimate daily exposure to air pollution all participants will wear a global positioning system GPS device and complete daily activity diaries for 5 days during the school year Fifty participants who have demonstrated compliance with study procedures will be selected to also wear the GPS devices for 5 days during the summer months
The study completion date listed in this record was obtained from the Completed Date entered in the Query View Report System QVR
This study will enroll children with asthma who live within 20 kilometers of the EPA Supersite in Fresno California Participants will have study visits twice a year for up to 2 ½ years At study entry participants will undergo a skin prick allergy test and complete a dietary questionnaire At each study visit a respiratory illness questionnaire will be completed and participants will undergo spirometry tests to measure lung function In addition to the twice yearly visits participants will take part in three 14-day sessions each year during which daily diaries will be completed and spirometry will be performed twice a day Study staff will gather detailed air pollution information from the Supersite mobile monitoring trailers and inside and outside the participants homes
Beginning in May 2006 participants will take part in only one study visit and two 14-day sessions each year Air pollution measurements will be obtained from only the Supersite To estimate daily exposure to air pollution all participants will wear a global positioning system GPS device and complete daily activity diaries for 5 days during the school year Fifty participants who have demonstrated compliance with study procedures will be selected to also wear the GPS devices for 5 days during the summer months
The study completion date listed in this record was obtained from the Completed Date entered in the Query View Report System QVR
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL081521-01A1 | NIH | None | httpsreporternihgovquickSearchR01HL081521-01A1 |