Ignite Creation Date:
2024-05-05 @ 4:52 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00339313
Status:
COMPLETED
Last Update Posted:
2017-07-02
First Post:
2006-06-19
Brief Title:
Food Intake and Appetite in the Children of Mothers With Diabetes
Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases NIDDK
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Food Intake and Appetite in the Children of Mothers With Diabetes
Status:
COMPLETED
Status Verified Date:
2011-06-24
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This protocol is for study of the effect of inhibition of parasympathetic outflow on insulin secretion and glucose metabolism Insulin secretion will be measured during infusions of escalating doses of atropine Other clinical parameters of parasympathetic inhibition by atropine will also be assessed
Detailed Description:
Children of mothers who had diabetes during pregnancy are at an increased risk of diabetes and obesity in later life effects partly mediated by the early environment experienced by the offspring of diabetic mothers in utero In this protocol we address why intra-uterine exposure to maternal diabetes might lead to later childhood obesity Previous studies of children of diabetic mothers have not detected any alteration in energy expenditure either as resting metabolic rate or physical activity We will now examine whether they are at an increased risk of obesity due to differences in food intake We will assess composition of the diet patterns of eating taste preference and physiological responses to a mixed meal No previous work in human subjects has addressed these issues
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| OH00-DK-N005 | None | None | None |