Ignite Creation Date:
2024-05-06 @ 12:32 PM
Last Modification Date:
2024-10-26 @ 1:00 PM
Study NCT ID:
NCT03787797
Status:
COMPLETED
Last Update Posted:
2022-11-03
First Post:
2018-12-21
Brief Title:
Epicardial Adipose Tissue Thickness PredIcts Obstructive Coronary Artery Disease in Acute Coronary Syndrome Patients
Sponsor:
University Hospital Essen
Organization:
University Hospital Essen
Study Overview
Official Title:
Epicardial Adipose Tissue Thickness PredIcts Obstructive Coronary Artery Disease in Acute Coronary Syndrome Patients
Status:
COMPLETED
Status Verified Date:
2022-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
EPIC-ACS
Brief Summary:
Epicardial adipose tissue EAT is a visceral adipose tissue that surrounds the heart and the coronary arteries It is metabolically active secreting pro- and anti-inflammatory mediators and cytokines With increasing EAT volume inflammatory activity increasing which suggests that EAT may locally influence atherosclerosis development in the coronary artery tree The amount of EAT is associated with cardiovascular disease risk factors as well as presence and progression of subclinical atherosclerosis Likewise EAT volume is increased in patient with prevalent and incident coronary artery disease manifestation In the setting of acute coronary syndrome EAT was found to be associated with the TIMI risk score and Syntax II score While CT imaging of the heart is the gold standard for EAT quantification transthoracic echocardiography allows for a quick and reliable assessment of EAT thickness as has been used in research studies and may qualify for routine EAT assessment in clinical routineHowever currently data on how quantification of EAT in clinical routine may impact patient management is lacking We aim to investigate whether quantification of EAT thickness via transthoracic echocardiography enables improved risk stratification in patients presenting with acute chest pain to the emergency department
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None