Ignite Creation Date:
2024-05-06 @ 12:26 PM
Last Modification Date:
2024-10-26 @ 12:58 PM
Study NCT ID:
NCT03754010
Status:
COMPLETED
Last Update Posted:
2018-11-27
First Post:
2018-11-15
Brief Title:
Does Hyaluronic Acid Affect Periodontal Treatment
Sponsor:
Yuzuncu Yıl University
Organization:
Yuzuncu Yıl University
Study Overview
Official Title:
Evaluation of Clinical and Biochemical Effects of Hyaluronic Acid on Periodontitis A Split-mouth Randomized-controlled Trial
Status:
COMPLETED
Status Verified Date:
2018-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Objective The aim of this study is to evaluate the effect of HA as an adjunct to scaling and root planning SRP on clinical parameters periodontal inflamed surface area PISA and adenosine deaminase ADA catalase CAT and glutathione GSH levels in gingival crevicular fluid GCF in patients with periodontitis
Detailed Description:
Design A total of 24 Stage II-III periodontitis patients will be included in this split-mouth randomized-controlled study The study population will be divided into four groups in Group 1 SRP SRP saline in Group 2 SRPHAgel SRP HA gel in Group 3 SRPHAmo SRP HA mouthrinse and in Group 4 SRPHAmoHAgel SRPHA mouthrinse HA gingival gel were applied At baseline and Week 4 periodontal clinical parameters and PISA will be calculated Also GCF amount will be collected to evaluate ADA CAT and GSH by spectrophotometric analysis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None