Ignite Creation Date:
2024-05-05 @ 4:51 PM
Last Modification Date:
2024-10-26 @ 9:24 AM
Study NCT ID:
NCT00320931
Status:
TERMINATED
Last Update Posted:
2021-06-09
First Post:
2006-04-28
Brief Title:
Assessment of Coronary Artery Disease by Hybrid PETCT
Sponsor:
University of Maryland Baltimore
Organization:
University of Maryland Baltimore
Study Overview
Official Title:
Assessment of Coronary Flow Reserve and CT Angiography By Hybrid PETCT Relation to Clinically Indicated SPECT Studies
Status:
TERMINATED
Status Verified Date:
2021-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
There have been many advances in the test used to look for heart disease An example of this newer technology is the Multislice CT scan MSCT and Positron Emission Tomography PET scans
The use of this type of combined scan may show early coronary artery disease or the degree of damaged heart muscle form a heart attack with a single exam It may help doctors to know who might benefit from heart surgery or angioplasty to increase the blood flow to the heart This type of detailed images has previously been available only through cardiac catheterization
The use of this type of combined scan may show early coronary artery disease or the degree of damaged heart muscle form a heart attack with a single exam It may help doctors to know who might benefit from heart surgery or angioplasty to increase the blood flow to the heart This type of detailed images has previously been available only through cardiac catheterization
Detailed Description:
Advances in Non-invasive Multislice CT Imaging Multislice CT MSCT and PET imaging are becoming more widely available and more useful in cardiac assessment MSCT provides quantification of coronary calcium as well as information about the structures of the coronary vessel walls and atherosclerotic plaques Multiple studies have demonstrated that MSCT provides information on coronary artery stenosis comparable to that obtained from invasive coronary angiography PET imaging provides functional data via the measurement of coronary flow reserve CFR CFR is a quantitative measure of the increase in coronary blood flow in response to vasodilation normal coronary flow is able to augment by three- to four-fold diseased coronary arteries show less ability to increase flow ie less CFR Assessment of CFR yields functional information about the significance of coronary disease and is often used clinically in conjunction with anatomic imaging to identify early atherosclerosis There is no current data evaluating the incremental value of hybrid PETCT assessment of CFR and coronary anatomy in relation to SPECT studies in the clinical setting
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None