Ignite Creation Date:
2024-05-05 @ 4:51 PM
Last Modification Date:
2024-10-26 @ 9:24 AM
Study NCT ID:
NCT00322205
Status:
COMPLETED
Last Update Posted:
2017-01-11
First Post:
2006-05-04
Brief Title:
Bio-behavioral Lung Cancer Prevention Program
Sponsor:
National Institutes of Health NIH
Organization:
National Institute on Drug Abuse NIDA
Study Overview
Official Title:
Bio-behavioral Lung Cancer Prevention Program
Status:
COMPLETED
Status Verified Date:
2006-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The overall goal of this research is to increase our understanding of the role of individual genetic differences in response to bupropion treatment and the psychobiological mechanisms by which genetic and treatment factors interact in the smoking cessation process The ultimate objective is to provide information necessary to match bupropion vs behavioral counseling cessation treatment to those smokers with the greatest need and likelihood of benefit This study is a double-blind randomized placebo-controlled clinical trial of bupropion HCL brand name Zyban in adult male and female smokers The factorial design includes one treatment factor bupropion 300 mgday counseling vs placebo counseling and several subject factors eg genotype personality Smoking history psychological status will be assessed at baseline and blood will be drawn for genotyping Bupropion or placebo will be delivered over a 10-week treatment period and subjects will be instructed to quit smoking after two weeks of medication week 3 of treatment All subjects will also receive a 7-week group behavioral smoking cessation treatment over an 11 week period This study may yield information that will help clinicians identify the most effective smoking cessation treatment for a particular patient based on hisher background
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None